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132173-07-0

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  • N-[(z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-n-ethylcyclohexanamine,hydrochloride

    Cas No: 132173-07-0

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  • N-[(z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-n-ethylcyclohexanamine,hydrochloride

    Cas No: 132173-07-0

  • USD $ 1.0-1.0 / Metric Ton

  • 1 Metric Ton

  • 100 Metric Ton/Day

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  • 132173-07-0 Structure

  • Basic information

    1. Product Name: SR 31747
    2. Synonyms: SR 31747;(Z)-N-[3-(3-CHLORO-4-CYCLOHEXYLPHENYL)PROP-2-ENYL]-N-ETHYLCYCLOHEXYLAMINE HYDROCHLORIDE;3-(3-Chloro-4-cyclohexylphenyl)-N-cyclohexyl-N-ethyl-2(Z)-propenylaMine;3-(3-Chloro-4-cyclohexylphenyl)-N-cyclohexyl-N-ethyl-2(Z)-propenylaMine hydrochloride;(Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine;HKHPCMBPASXYGP-KVVVOXFISA-N
    3. CAS NO:132173-07-0
    4. Molecular Formula: C23H35Cl2N
    5. Molecular Weight: 396.4367
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 132173-07-0.mol
    9. Article Data: 1

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 479.9°C at 760 mmHg
    3. Flash Point: 244.1°C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 2.26E-09mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: SR 31747(CAS DataBase Reference)
    11. NIST Chemistry Reference: SR 31747(132173-07-0)
    12. EPA Substance Registry System: SR 31747(132173-07-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 132173-07-0(Hazardous Substances Data)

132173-07-0 Usage

Description

SR 31747 is a potent and selective inhibitor of the sodium-calcium exchanger, a lipophilic molecule that can penetrate cell membranes and regulate intracellular calcium levels. It has demonstrated antiarrhythmic effects and potential neuroprotective properties, making it a promising molecule for therapeutic applications in cardiovascular and neurological disorders.

Uses

Used in Pharmaceutical Industry:
SR 31747 is used as an antiarrhythmic agent for its ability to inhibit the reverse mode of the sodium-calcium exchanger, which helps in the treatment of cardiac arrhythmias.
Used in Neurological Applications:
SR 31747 is used as a neuroprotective agent for its potential to protect against conditions such as ischemic stroke and neurodegenerative diseases by maintaining intracellular calcium homeostasis and reducing neuronal damage.

Check Digit Verification of cas no

The CAS Registry Mumber 132173-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,1,7 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 132173-07:
(8*1)+(7*3)+(6*2)+(5*1)+(4*7)+(3*3)+(2*0)+(1*7)=90
90 % 10 = 0
So 132173-07-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H34ClN.ClH/c1-2-25(21-13-7-4-8-14-21)17-9-10-19-15-16-22(23(24)18-19)20-11-5-3-6-12-20;/h9-10,15-16,18,20-21H,2-8,11-14,17H2,1H3;1H/b10-9-;

132173-07-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(Z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-N-ethylcyclohexanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names (Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132173-07-0 SDS

132173-07-0Upstream product

132173-07-0Downstream Products

132173-07-0Related news

The sigma ligand SR 31747 (cas 132173-07-0) prevents the development of acute graft-versus-host disease in mice by blocking IFN-γ and GM-CSF mRNA expression08/03/2019

SR 31747 is a sigma ligand which prevents the development of acute graft-versus-host reaction (GvHR) in hybrid B6D2F1 mice injected with C57BL/6 parental spleen cells. In the present study, we showed that this drug dramatically impaired the GvHR-associated increase in the numbers of both B-lymph...detailed

132173-07-0Relevant articles and documents

Benzene derivatives, their preparation and pharmaceutical compositions in which they are present

-

, (2008/06/13)

The present invention relates to compounds of the formula STR1 in which: p1 R1 is hydrogen or a halogen atom; R2 is a cyclohexyl or a phenyl; R3 is a (C3 -C6) cycloalkyl; R4 is hydrogen, (C

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