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  • 13139-12-3 Structure
  • Basic information

    1. Product Name: BOC-OSU
    2. Synonyms: BOC-OSU;BOC-ONSU;LABOTEST-BB LT00645757;TERT-BUTYL N-SUCCINIMIDYL CARBONATE;T-BUTYL N-SUCCINIMIDO CARBONATE;T-BUTYL N-SUCCINIMIDYL CARBONATE;N-TERT-BUTYLOXYCARBONYLOXY-SUCCINIMIDE;N-(TERT-BUTOXYCARBONYLOXY)SUCCINIMIDE
    3. CAS NO:13139-12-3
    4. Molecular Formula: C9H13NO5
    5. Molecular Weight: 215.2
    6. EINECS: 236-071-1
    7. Product Categories: N/A
    8. Mol File: 13139-12-3.mol
    9. Article Data: 1
  • Chemical Properties

    1. Melting Point: ~95 °C (dec.)
    2. Boiling Point: 272.834 °C at 760 mmHg
    3. Flash Point: 118.806 °C
    4. Appearance: White/Powder
    5. Density: 1.268 g/cm3
    6. Vapor Pressure: 0.00594mmHg at 25°C
    7. Refractive Index: 1.493
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. Sensitive: Moisture Sensitive
    11. BRN: 1536756
    12. CAS DataBase Reference: BOC-OSU(CAS DataBase Reference)
    13. NIST Chemistry Reference: BOC-OSU(13139-12-3)
    14. EPA Substance Registry System: BOC-OSU(13139-12-3)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22-43
    3. Safety Statements: 36/37-60-37-24
    4. WGK Germany: 2
    5. RTECS:
    6. F: 10-21
    7. TSCA: Yes
    8. HazardClass: N/A
    9. PackingGroup: N/A
    10. Hazardous Substances Data: 13139-12-3(Hazardous Substances Data)

13139-12-3 Usage

Description

BOC-OSU, a bifunctional chemical reagent, is widely recognized for its role in bioconjugation and protein modification. It features a BOC (tert-butyloxycarbonyl) group and an OSU (N-hydroxysuccinimide ester) group, which together enable the protection and stable bonding of amine groups in proteins. This versatile reagent is instrumental in the synthesis of peptide and protein conjugates, as well as in the immobilization of proteins on solid surfaces for various bioanalytical and diagnostic applications.

Uses

Used in Bioconjugation:
BOC-OSU is used as a coupling agent for the formation of stable amide bonds between proteins and other biomolecules. Its OSU group reacts with amine groups, facilitating the creation of peptide and protein conjugates.
Used in Protein Modification:
In the field of protein modification, BOC-OSU serves as a protective agent for amine groups, thanks to its BOC group. This protection is crucial during the modification process to prevent unwanted side reactions.
Used in Bioanalytical Applications:
BOC-OSU is utilized as a reagent for the immobilization of proteins onto solid surfaces. This immobilization is essential for various bioanalytical techniques, enhancing the sensitivity and specificity of assays.
Used in Diagnostic Applications:
In diagnostics, BOC-OSU plays a significant role in the development of diagnostic tools. Its ability to form stable bonds and protect amine groups contributes to the creation of reliable and effective diagnostic assays.
Used in Pharmaceutical Development:
BOC-OSU is employed in the synthesis of drug conjugates, where its ability to form stable bonds with amine groups is crucial for the development of targeted therapeutic agents.
Used in Research and Development:
In research settings, BOC-OSU is a valuable tool for the modification and functionalization of proteins and peptides, enabling scientists to explore new avenues in molecular biology and biotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 13139-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,3 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13139-12:
(7*1)+(6*3)+(5*1)+(4*3)+(3*9)+(2*1)+(1*2)=73
73 % 10 = 3
So 13139-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO5/c1-9(2,3)14-8(13)15-10-6(11)4-5-7(10)12/h4-5H2,1-3H3

13139-12-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (H54493)  N-(tert-Butoxycarbonyloxy)succinimide, 98+%   

  • 13139-12-3

  • 1g

  • 156.0CNY

  • Detail
  • Alfa Aesar

  • (H54493)  N-(tert-Butoxycarbonyloxy)succinimide, 98+%   

  • 13139-12-3

  • 5g

  • 784.0CNY

  • Detail
  • Alfa Aesar

  • (H54493)  N-(tert-Butoxycarbonyloxy)succinimide, 98+%   

  • 13139-12-3

  • 25g

  • 2608.0CNY

  • Detail
  • Aldrich

  • (20430)  Boc-OSu  ≥98.0% (CHN)

  • 13139-12-3

  • 20430-5G

  • 1,668.42CNY

  • Detail
  • Aldrich

  • (20430)  Boc-OSu  ≥98.0% (CHN)

  • 13139-12-3

  • 20430-25G

  • 6,084.00CNY

  • Detail

13139-12-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl N-succinimidyl carbonate

1.2 Other means of identification

Product number -
Other names N-(tert-Butoxycarbonyloxy)succinimide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13139-12-3 SDS

13139-12-3Upstream product

13139-12-3Relevant articles and documents

Frankel et al.

, p. 4765 (1966)

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