131379-14-1

Basic information

• Product Name: 4-CYANOPHENYLZINC BROMIDE
• Synonyms: 4-CYANOPHENYLZINC BROMIDE;4-CYANOPHENYLZINC BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN;4-cyanophenylzinc bromide solution;(p-Cyanophenyl)bromozinc;4-(Bromozincio)benzonitrile;Bromo(4-cyanophenyl) zinc;4-Cyanophenylzinc bromide solution 0.5 in THF;4-Cyanophenylzinc broMide, 0.5M in THF, packaged under Argon in resealable CheMSeal^t bottles
• CAS NO: 131379-14-1
• Molecular Formula: C₇H₄BrNZn
• Molecular Weight: 247.41
• Product Categories: Alkyl;Organozinc Halides;Reike and Organozinc Reagents;Aryl;Chemical Synthesis;Organometallic Reagents;Organozinc Halides;Rieke and Organozinc Reagents
• Mol File: 131379-14-1.mol
• Article Data: 7

Chemical Properties

• Flash Point: 1 °F
• Appearance: /
• Density: 0.98 g/mL at 25 °C
• Storage Temp.: 2-8°C
• Water Solubility: Reacts with water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-CYANOPHENYLZINC BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANOPHENYLZINC BROMIDE(131379-14-1)
• EPA Substance Registry System: 4-CYANOPHENYLZINC BROMIDE(131379-14-1)

Safety Data

• Hazard Codes: F,Xn
• Statements: 19-22-36/38-40-36/37-14-11
• Safety Statements: 16-26-33-36-36/37
• RIDADR: UN 3399 4.3/PG 2
• WGK Germany: 1
• HazardClass: 4.3
• Hazardous Substances Data: 131379-14-1(Hazardous Substances Data)

Usage

Uses

4-Cyanophenylzinc bromide is used to produce biphenyl-4-carbonitrile.

InChI:InChI=1/C7H4N.BrH.Zn/c8-6-7-4-2-1-3-5-7;;/h2-5H;1H;/q;;+1/p-1/rC7H4BrNZn/c8-10-7-3-1-6(5-9)2-4-7/h1-4H

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 7440-66-6 zinc 
• 7699-45-8 zinc dibromide 

Downstream Products

• 22836-30-2 4,4',4''-phosphanetriyltribenzonitrile 
• 957770-94-4 (-)-(R)-4-(hydroxy(phenyl)methyl)benzonitrile 
• 1215285-78-1 (S)-4-[hydroxy(phenyl)methyl]benzonitrile 
• 1591-30-6 (1,1'-biphenyl)-4,4'-dicarbonitrile 
• 1456546-61-4 4-(6-bromopyridin-2-yl)benzonitrile 
• 1204-85-9 4-(piperidin-1-yl)benzonitrile 
• 1414890-64-4 (E)-4-(1-butyl-hex-1-enyl)-benzonitrile 
• 862170-57-8 4-[(4,6-dichloro-3-pyridinyl)carbonyl]benzonitrile 
• 1104453-44-2 4-(2-(4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidin-1-yl)pyrimidin-5-yl)benzonitrile 
• 901310-23-4 4-[(4-methoxy-phenyl)-phenyl-phosphanyl]-benzonitrile 
• 27634-88-4 4-cyclohexyl-1-cyanobenzene 

Relevant articles and documents

Cobalt-Catalyzed Oxidative Homocoupling of Arylzinc Species

A novel procedure for the synthesis of functionalized symmetrical biaryl compounds is described. The reaction proceeds via the oxidative homocoupling of arylzinc species formed by cobalt catalysis in the presence of air or p-benzoquinone depending on the nature of the functional group.

Cobalt-catalyzed electrophilic amination of arylzincs with N-chloroamines

Roles reversed: An efficient cobalt-catalyzed electrophilic amination of arylzinc reagents has been achieved. A variety of functionalized arylzincs and N-chloroamines were coupled under mild conditions (see scheme). Both secondary and tertiary arylamines were obtained in moderate to excellent yields. Copyright

Microwave-assisted Negishi and Kumada cross-coupling reactions of aryl chlorides

Rapid Pd or Ni-catalyzed microwave-accelerated Negishi and Kumada cross-coupling reactions of aryl chlorides in solution and on solid phase are reported.