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  • PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)/ LIDE PHARMA- Factory supply / Best price

    Cas No: 130855-30-0

  • USD $ 10.0-10.0 / Gram

  • 1 Gram

  • 10 Metric Ton/Day

  • LIDE PHARMACEUTICALS LIMITED
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  • 130855-30-0 Structure
  • Basic information

    1. Product Name: PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)
    2. Synonyms: PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE);(+)-trans-Paroxetine hydrochloride;Paroxetine Related CoMpound C;(3R,4S)-3-[(1,3-Benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)piperidine Hydrochloride;(3R-trans)-3-[(1,3-Benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)piperidine Hydrochloride;ent-Paroxetine Hydrochloride;(3R,4S)-3-[(1,3-benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)piperidine hydrochloride (aka Paroxetine iMpurity D);Paroxetine HCl EP IMp D (USP RC C)
    3. CAS NO:130855-30-0
    4. Molecular Formula: C19H21ClFNO3
    5. Molecular Weight: 365.8263432
    6. EINECS: 208-028-7
    7. Product Categories: Aromatics;Heterocycles;Impurities;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 130855-30-0.mol
    9. Article Data: 29
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
    8. Solubility: Methanol (Slightly), Water (Slightly)
    9. Stability: Hygroscopic
    10. CAS DataBase Reference: PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)(CAS DataBase Reference)
    11. NIST Chemistry Reference: PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)(130855-30-0)
    12. EPA Substance Registry System: PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)(130855-30-0)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 41-62
    3. Safety Statements: 26-39
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 130855-30-0(Hazardous Substances Data)

130855-30-0 Usage

Description

PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) is an enantiomeric impurity of Paroxetine (P205750), which is a selective serotonin reuptake inhibitor (SSRI) commonly used as an antidepressant medication. PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) is characterized by its specific molecular structure and properties, which differentiate it from the main active ingredient in Paroxetine.

Uses

Used in Pharmaceutical Industry:
PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) is used as an enantiomeric impurity for the development and quality control of Paroxetine (P205750). Its presence in the final drug product needs to be monitored and controlled to ensure the safety, efficacy, and purity of the medication. This is important because enantiomeric impurities can sometimes have different or even adverse effects compared to the main active ingredient.
Additionally, understanding the properties and behavior of this compound can contribute to the optimization of the manufacturing process and the development of new, more effective medications with fewer side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 130855-30-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,8,5 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 130855-30:
(8*1)+(7*3)+(6*0)+(5*8)+(4*5)+(3*5)+(2*3)+(1*0)=110
110 % 10 = 0
So 130855-30-0 is a valid CAS Registry Number.

130855-30-0 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0000256)  Paroxetine impurity D  European Pharmacopoeia (EP) Reference Standard

  • 130855-30-0

  • Y0000256

  • 1,880.19CNY

  • Detail

130855-30-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,4S)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine,hydrochloride

1.2 Other means of identification

Product number -
Other names Paroxetine impurity D

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130855-30-0 SDS

130855-30-0Downstream Products

130855-30-0Relevant articles and documents

Total synthesis of (±)-paroxetine by diastereoconvergent cobalt-catalysed arylation

Despiau, Carole F.,Dominey, Andrew P.,Harrowven, David C.,Linclau, Bruno

, p. 4335 - 4341 (2014)

A total synthesis of paroxetine is reported, with a diastereoselective and diastereoconvergent cobalt-catalysed sp3-sp2 coupling reaction involving a 3-substituted 4-bromo-N-Boc-piperidine (Boc = tert-butoxycarbonyl) substrate as a key step. A 9:1 diastereoselectivity was obtained, while a control experiment involving a conformationally locked 3-substituted 4-bromo-tert-butyl cyclohexane ring proceeded with essentially complete stereoselectivity.

Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis

Krautwald, Simon,Schafroth, Michael A.,Sarlah, David,Carreira, Erick M.

, p. 3020 - 3023 (2014/03/21)

We describe the fully stereodivergent, dual catalytic α-allylation of linear aldehydes. The reaction proceeds via direct iridium-catalyzed substitution of racemic allylic alcohols with enamines generated in situ. The use of an Ir(P,olefin) complex and a diarylsilyl prolinol ether as catalysts in the presence of dimethylhydrogen phosphate as the promoter proved to be crucial for achieving high enantio- and diastereoselectivity (>99% ee, up to >20:1 dr). The utility of the method is demonstrated in a concise enantioselective synthesis of the antidepressant (-)-paroxetine.

SULFATED GALACTANS WITH ANTITHROMBOTIC ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING OR PROPHYLAXIS OF ARTERIAL OR VENOUS THROMBOSIS, METHOD OF EXTRACTION AND USE THEREOF

-

Page/Page column 6-7, (2009/12/23)

The present invention relates to low molecular weight sulfated galactans, obtained from algae, particularly genus Botryocladia, preferably species Botryocladia occidentallis, which have no effect on the factor XII activation of the clotting cascade, having antithrombotic heparinoid activity. The present invention also refers to a pharmaceutical composition comprising said sulfated galactans and the use thejreof, as heparin substitute, in the treatment or prophylaxis of arterial or venous thrombosis in humans and animals. Furthermore, the present invention provides a method of extraction of the said sulfated galactans.

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