129441-47-0

Basic information

• Product Name: (3R,4R)-1-(benzyloxycarbonyl-1-hydroxymethyl)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one
• CAS NO: 129441-47-0
• Molecular Weight: 523.656
• Mol File: 129441-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-1-(benzyloxycarbonyl-1-hydroxymethyl)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-1-(benzyloxycarbonyl-1-hydroxymethyl)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one(129441-47-0)
• EPA Substance Registry System: (3R,4R)-1-(benzyloxycarbonyl-1-hydroxymethyl)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one(129441-47-0)

Safety Data

• Hazardous Substances Data: 129441-47-0(Hazardous Substances Data)

Upstream product

• 52709-42-9 benzylglyoxylate 
• 129441-46-9 (3R,4R)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one 
• 93713-40-7 Glycerin-monoacetat 
• 123657-02-3 (3R,4R)-4-allyloxy-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>azetidin-2-one 
• 129441-44-7 (3R,4R)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(2,3-epoxypropyloxy)azetidin-2-one 
• 129441-45-8 (3R,4R)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-hydroxypropane-1-oxy)azetidin-2-one 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 

Downstream Products

• 129441-48-1 (3R,4R)-1-(benzyloxycarbonyl-1-chloromethyl)-3-<(1R)-1-tert-butyldimethylsilyloxyethyl>-4-(3-acetoxy-2-oxopropane-1-oxy)azetidin-2-one 
• 129441-61-8 benzyl 7α-<(1R)-1-hydroxyethyl>-3-cyano-1-oxa-3-cephem-4-carboxylate 
• 129441-62-9 benzyl 7α-<(1R)-1-hydroxyethyl>-3-formyl-1-oxa-3-cephem-4-carboxylate 
• 129441-63-0 benzyl 7α-<(1R)-1-hydroxyethyl>-3-carbamoyl-1-oxa-3-cephem-4-carboxylate 
• 129441-64-1 benzyl 7α-<(1R)-1-hydroxyethyl>-3-methoxycarbonyl-1-oxa-3-cephem-4-carboxylate 
• 129441-52-7 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-formyl-1-oxa-3-cephem-4-carboxylate 
• 129441-51-6 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-hydroxymethyl-1-oxa-3-cephem-4-carboxylate 
• 129441-57-2 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-cyano-1-oxa-3-cephem-4-carboxylate 
• 129441-53-8 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-carboxyl-1-oxa-3-cephem-4-carboxylate 
• 129441-54-9 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-carbamoyl-1-oxa-3-cephem-4-carboxylate 
• 129441-56-1 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-hydroxyiminomethyl-1-oxa-3-cephem-4-carboxylate 
• 129441-55-0 benzyl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-methoxycarbonyl-1-oxa-3-cephem-4-carboxylate 
• 129441-59-4 benzhydryl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-chloromethyl-1-oxa-3-cephem-4-carboxylate 
• 129441-58-3 benzhydryl 7α-<(1R)-1-tert-butyldimethylsilyloxyethyl>-3-hydroxymethyl-1-oxa-3-cephem-4-carboxylate 

Relevant articles and documents

1-OXACEPHEMS WITH THE THIENAMYCIN-TYPE SIDE CHAIN (1). SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 7&α--1-OXACEPHEMS BEARING ELECTRON-WITHDRAWING GROUPS

1-Oxacephem derivatives, 2a-d, bearing the hydroxyethyl group at C7α and some electron-withdrawing groups at C3 were synthesized and tested for antibacterial activity.It was found that some of these compounds, in particular, 7α-hydro