129397-36-0Relevant articles and documents
A Stereoselective Synthesis of the (2R,3S)- and (2S,3R)-3-Amino-2-hydroxybutyric Acid Derivatives, the Key Components of a Renin Inhibitor and Bestatin
Kobayashi, Yuko,Takemoto, Yoshiji,Kamijo, Tetsuhide,Harada, Hiromu,Ito, Yoshio,Terashima, Shiro
, p. 1853 - 1868 (2007/10/02)
The title synthesis was achieved by featuring the -cycloaddition reaction of benzyloxyketene with a chiral imine derived from methyl (R)- or (S)-mandelate, alcoholysis of the formed 3,4-cis disubstituted β-lactam under acidic conditions, and reductiv