1283096-72-9 Usage
Description
(2S)-2-(2,4,5-trifluorobenzyl)-oxirane, also known as (S)-(+)-2-(2,4,5-trifluorophenyl)oxirane, is a chemical compound with the molecular formula C9H7F3O. It is an epoxide, which is a cyclic ether with a three-membered ring. (2S)-2-(2,4,5-trifluorobenzyl)-oxirane is characterized by its trifluorobenzyl group, making it a valuable tool for the preparation of complex molecules with high selectivity and efficiency. However, it is important to exercise caution when handling this compound due to its potential harmful effects if swallowed, inhaled, or in contact with skin, and its potential to cause irritation to the respiratory system and skin.
Uses
Used in Organic Synthesis:
(2S)-2-(2,4,5-trifluorobenzyl)-oxirane is used as a reagent in organic synthesis for the production of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and properties make it a versatile component in the synthesis of a wide range of compounds.
Used as a Chiral Building Block:
In the field of asymmetric synthesis, (2S)-2-(2,4,5-trifluorobenzyl)-oxirane serves as a chiral building block for the synthesis of biologically active compounds. Its enantioselective properties are valuable for creating complex molecules with specific biological activities and selectivity.
Used in Pharmaceutical Industry:
(2S)-2-(2,4,5-trifluorobenzyl)-oxirane is used as a key intermediate in the development of new pharmaceuticals. Its ability to form complex molecules with high selectivity makes it an essential component in the synthesis of drugs with improved efficacy and reduced side effects.
Used in Agrochemical Industry:
(2S)-2-(2,4,5-trifluorobenzyl)-oxirane is also utilized in the agrochemical industry for the synthesis of pesticides and other agrochemical products. Its unique properties allow for the development of more effective and targeted agrochemicals with reduced environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 1283096-72-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,3,0,9 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1283096-72:
(9*1)+(8*2)+(7*8)+(6*3)+(5*0)+(4*9)+(3*6)+(2*7)+(1*2)=169
169 % 10 = 9
So 1283096-72-9 is a valid CAS Registry Number.
1283096-72-9Relevant articles and documents
METHOD FOR PREPARING INTERMEDIATE OF SITAGLIPTIN USING CHIRAL OXIRANE
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Page/Page column 13, (2011/04/25)
Disclosed is: a novel, simple and low-cost method for preparing 3-hydroxy-4-(2,4,5-trifluorophenyl)-butyric acid, particularly (3S)-3-hydroxy-4-(2,4,5-trifluorophenyl)-butyric acid, which is used as a key intermediate in the preparation of sitagliptin.
METHOD FOR PREPARING SITAGLIPTIN AND AMINE SALT INTERMEDIATES USED THEREIN
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Page/Page column 12, (2011/09/19)
The present invention relates to a method for preparing sitagliptin by using an amine salt of (3R)-3-azido-4-(2,4,5-trifluorophenyl)-butyric acid (formula (V)) in a high yield and purity, and amine salt intermediates used therein.
