1270171-48-6Relevant articles and documents
Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
Goncalves, Renato S.,Abdelnur, Patricia V.,Santos, Vanessa G.,Simas, Rosineide C.,Eberlin, Marcos N.,Magalhaes, Alvicler,Perez Gonzalez, Eduardo R.
experimental part, p. 197 - 204 (2011/10/05)
Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination SNAr mechanism was confirmed by NMR and MS measurements. Graphical Abstract: [Figure not available: see fulltext.]