1261181-18-3Relevant articles and documents
Design of a novel class of biphenyl CETP inhibitors
Lu, Zhijian,Napolitano, Joann B.,Theberge, Ashleigh,Ali, Amjad,Hammond, Milton L.,Tan, Eugene,Tong, Xinchun,Xu, Suoyu S.,Latham, Melanie J.,Peterson, Laurence B.,Anderson, Matt S.,Eveland, Suzanne S.,Guo, Qiu,Hyland, Sheryl A.,Milot, Denise P.,Chen, Ying,Sparrow, Carl P.,Wright, Samuel D.,Sinclair, Peter J.
scheme or table, p. 7469 - 7472 (2011/01/12)
A new class of CETP inhibitors was designed and prepared. These compounds are potent both in vitro and in vivo. The most active compound (12d) has shown an ability to raise HDL significantly in transgenic mouse PD model.
