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  • 1248-42-6 Structure
  • Basic information

    1. Product Name: methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride
    2. Synonyms: methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride;PITOFENONEHYDROCHLORIDE(FORR&DONLY);2-[4-(2-piperidinoethoxy)benzoyl]benzoic acid methyl ester hydrochloride;methyl 2-[4-(2-piperidin-1-ylethoxy)benzoyl]benzoate hydrochloride;methyl 2-[4-(2-piperidin-1-ylethoxy)phenyl]carbonylbenzoate hydrochloride;Pitophenone hydrochloride
    3. CAS NO:1248-42-6
    4. Molecular Formula: C10H16O4
    5. Molecular Weight: 403.89914
    6. EINECS: 214-999-8
    7. Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 1248-42-6.mol
    9. Article Data: 12
  • Chemical Properties

    1. Melting Point: 169-170°C
    2. Boiling Point: 512 °C at 760 mmHg
    3. Flash Point: 263.4 °C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 1.35E-10mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: -20°C Freezer
    9. Solubility: N/A
    10. CAS DataBase Reference: methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride(1248-42-6)
    12. EPA Substance Registry System: methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride(1248-42-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1248-42-6(Hazardous Substances Data)

1248-42-6 Usage

Description

Methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride is a complex organic compound with a unique chemical structure that features a benzoyl group connected to a methyl ester and a piperidinoethoxybenzoyl moiety. methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride exhibits a white solid form and possesses specific chemical properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
Methyl 2-[4-[2-piperidinoethoxy]benzoate hydrochloride is used as an antispasmodic agent for its ability to inhibit acetylcholine-induced contractions, similar to the properties of Pitofenone. This makes it a potential candidate for the treatment of various conditions that involve muscle spasms or involuntary contractions.
Used in Drug Combinations:
Methyl 2-[4-[2-piperidinoethoxy]benzoate hydrochloride can be used in combination with other drugs such as Diclofenac, Pitofenone, and Fenpiverinium to enhance antispasmodic activity. This combination may provide a more effective treatment option for patients suffering from muscle spasms or related conditions.
Used in Drug Delivery Systems:
Due to its unique chemical properties, methyl 2-[4-[2-piperidinoethoxy]benzoate hydrochloride may also be utilized in the development of drug delivery systems. These systems can be designed to improve the bioavailability, targeting, and overall efficacy of the compound when used in various therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1248-42-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1248-42:
(6*1)+(5*2)+(4*4)+(3*8)+(2*4)+(1*2)=66
66 % 10 = 6
So 1248-42-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H25NO4.ClH/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23;/h3-4,7-12H,2,5-6,13-16H2,1H3;1H

1248-42-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-[4-[2-piperidinoethoxy]benzoyl]benzoate hydrochloride

1.2 Other means of identification

Product number -
Other names 2-[4-(2-Piperidino-aethoxy)-benzoyl]-benzoesaeure-methylester,Hydrochlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1248-42-6 SDS

1248-42-6Downstream Products

1248-42-6Relevant articles and documents

An unexpected reaction of camphor with sodium metal

Khanvilkar, Aditya N.,Gupta, Riddhi,Bedekar, Ashutosh V.

, p. 1327 - 1331 (2016/02/23)

Reaction of camphor with sodium metal at elevated temperature in refluxing THF or toluene, furnishes an unexpected product. The product has been identified by spectral analysis and its structure confirmed by single crystal X-ray diffraction study. A preliminary mechanistic explanation has been suggested to explain this reaction.

Synthesis and characterization of Ru(II) and Ir(III) complexes that bear camphoric 1,3-diamine ligands

Yu, Jun-Lai,Guo, Rong,Wang, Hui,Li, Zhan-Ting,Zhang, Dan-Wei

, p. 36 - 41 (2014/07/22)

Two rigid N-monosulfonylated 1,3-diamine ligands have been prepared starting from commercially available d-camphor through three steps. Their reactions with [Ru(η6-arene)(μ-Cl)Cl]2 (arene = p-cymene or C6H5CO2Et) or [Ir(η 5-C5Me5)(μ-Cl)Cl]2 afforded five new complexes. The structures of one monosulfonamide 1,3-diamine ligand and three organometallic complexes were confirmed by X-ray crystallography.

Synthesis of 1,11,11-trimethyl-3,6-diazotricyclo [6.2.1.0 2,7]undeca-2,6-diene and 1,15,15-trimethyl-3,10-diazotetracyclo[10.2. 1.02,11.04,9]pentadeca-2,4(9),5,7,10-pentaene from camphoroquinone enantiomers

Adamenko,Frolova,Panteleeva,Kuchin

, p. 59 - 62 (2008/02/12)

Optically active camphordihydro-2,3-pyrazine and camphorquinoxaline were prepared from camphoroquinone enantiomers. It was shown that (1S,4R)-(+)-camphoroquinone was formed by oxidation of (1S,3R, 4R)-(-)-3-bromocamphor and (1R,4S)-(-)-camphoroquinone from (1R,3S, 4S)-(+)-3-bromocamphor, respectively. Camphor anhydride was a side product (6-10%) of the reaction. Springer Science+Business Media, Inc. 2007.

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