124338-53-0

Basic information

• Product Name: 2-Butanol, 3-(phenylmethoxy)-, (2S,3R)-
• CAS NO: 124338-53-0
• Molecular Formula: C11H16O2
• Molecular Weight: 180.247
• Mol File: 124338-53-0.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 2-Butanol, 3-(phenylmethoxy)-, (2S,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanol, 3-(phenylmethoxy)-, (2S,3R)-(124338-53-0)
• EPA Substance Registry System: 2-Butanol, 3-(phenylmethoxy)-, (2S,3R)-(124338-53-0)

Safety Data

• Hazardous Substances Data: 124338-53-0(Hazardous Substances Data)

Upstream product

• 53346-05-7 2-(benzyloxy)propanal 
• 2747-38-8 methyltrichlorotitanium 
• 917-54-4 methyllithium 
• 75-16-1 methylmagnesium bromide 
• 113133-46-3 3-(phenylmethoxy)butan-2-one 
• 97203-22-0 (-)-(S)-3-(phenylmethoxy)-2-butanone 
• 273400-78-5 (4R,5S)-4,5-dimethyl-2-phenyl-1,3-dioxolane 
• 271578-41-7 (1R,4S,5R,6R)-5-[(S)-((1S,2R)-2-Benzyloxy-1-methyl-propoxy)-methoxy-methyl]-6-phenyl-bicyclo[2.2.1]hept-2-ene 
• 185961-43-7 4-Nitro-benzoic acid (1S,2R)-2-benzyloxy-1-methyl-propyl ester 
• 124338-52-9 (2R,3R)-3-(phenylmethoxy)-2-butanol 
• 100-52-7 benzaldehyde 
• 75281-80-0 4,5-dimethyl-2-phenyl-(2α,4α,5β)-1,3-dioxolane 
• 100-39-0 benzyl bromide 

Downstream Products

• 170985-78-1 [2-((1S,2R)-2-Benzyloxy-1-methyl-propoxymethoxy)-ethyl]-trimethyl-silane 

Relevant articles and documents

Asymmetric Induction by a Nitrogen14N/15N Isotopomer in Conjunction with Asymmetric Autocatalysis

Chirality arising from isotope substitution, especially with atoms heavier than the hydrogen isotopes, is usually not considered a source of chirality in a chemical reaction. An N2,N2,N3,N3-tetramethyl-2,3-butan

Reductive cleavage of acetals and ketals with 9-borabicyclo[3.3.1]nonane

The reductive cleavage of benzaldehyde acetals and acetophenone ketals with the air-stable crystalline 9-borabicyclo[3.3.1]-nonane dimer provides monobenzylated ether derivatives of diols and 1,2-oxygen-transposed β-phenethyl alcohols, respectively. The boron moiety is effectively recovered through simple procedures which involve convenient air-stable reagents and boron byproducts. The process is particularly selective for 1,3-diols giving the more substituted monobenzyl ether derivatives exclusively. With acetophenone ketals both reduction and elimination occur, permitting 9-BBN-H to hydroborate the resulting styrene to produce 1,2-oxygen-transposed β-phenethyl alcohols cleanly. Potential applications of this new process were illustrated with the synthesis of the hallucinogen, mescaline, and the analgesic, ibufenac.

Hydrogenation of α-Keto Ethers: Dynamic Kinetic Resolution with a Heterogeneous Modified Catalyst and a Heterogeneous Base

The first successful example of the asymmetric hydrogenation of substituted α-keto ethers with Cinchona-modified Pt/Al2O3 is reported. In the absence of an additional base, kinetic resolution of the racemic starting material was observed with high diastereoselectivity and ee's up to 98% at conversions of a strong reaction acceleration but racemic product. Immobilization of OH- on solid ion exchangers resulted in the desired dynamic kinetic resolution, and ee's of >80% were obtained at >95% conversion. These effects are rationalized on the basis of a simple kinetic and structural model.