1242175-40-1 Usage
Description
Aprepitant is a pharmaceutical compound that belongs to the class of antiemetic agents, specifically a substance P/neurokinin 1 (NK1) receptor antagonist. It is designed to prevent and treat nausea and vomiting by blocking the action of a natural substance in the brain that triggers these symptoms. Aprepitant is available in capsule form and is typically taken orally before chemotherapy or surgery.
Uses
Used in Oncology:
Aprepitant is used as an antiemetic agent for the prevention of chemotherapy-induced nausea and vomiting. It is often combined with other medications to provide a more effective treatment for managing these side effects of chemotherapy.
Used in Post-operative Care:
Aprepitant is also used as an antiemetic agent to prevent post-operative nausea and vomiting, helping patients recover more comfortably after surgery.
Common side effects of aprepitant may include drowsiness, dizziness, and constipation. However, it is considered an effective and well-tolerated medication for preventing nausea and vomiting in specific clinical settings, such as oncology and post-operative care.
Check Digit Verification of cas no
The CAS Registry Mumber 1242175-40-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,2,1,7 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1242175-40:
(9*1)+(8*2)+(7*4)+(6*2)+(5*1)+(4*7)+(3*5)+(2*4)+(1*0)=121
121 % 10 = 1
So 1242175-40-1 is a valid CAS Registry Number.
1242175-40-1Relevant articles and documents
Synthesis of all enantiomerically pure diastereomers of aprepitant
Gangula, Srinivas,Elati, Chandrashekhar R.,Mudunuru, Satish Varma,Nardela, Anitha,Dongamanti, Ashok,Bhattacharya, Apurba,Bandichhor, Rakeshwar
experimental part, p. 2254 - 2268 (2010/09/11)
Syntheses of all eight enantiomerically pure diastereomers of aprepitant and assignment of absolute configuration at newly generated stereocenters by NMR and X-ray crystallographic analysis were achieved. Copyrigh
