123312-89-0Relevant articles and documents
Method for preparing pymetrozine
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Paragraph 0051; 0055; 0060; 0065, (2018/11/22)
The invention discloses a method for preparing pymetrozine with an aim to provide a synthesis method short in reaction route of the pymetrozine, small in environmental pollution and simple in technology operation, and belongs to the technical field of organic synthesis. The method includes the steps of 1), allowing dimethyl carbonate serving as a raw material to be subjected to hydrazinolysis withhydrazine hydrate to obtain carbazide; 2), subjecting carbazide and smoke aldehyde to condensation reaction to obtain (E)-N'-(pyridine-3-kiya methyl) hydrazine carbon hydrazide; 3), subjecting (E)-N'-( pyridine-3-kiya methyl) hydrazine carbon hydrazide and chloroacetone to condensation reaction to obtain (E)-N'-(Z)-1-chloropropyl-2-subunit)-2-(pyridine-3-kiya methyl) diazanyl-1-carbohydrazide; 4), subjecting (E)-N'-(Z)-1-chloropropyl-2-subunit)-2-(pyridine-3-kiya methyl) diazanyl-1-carbohydrazide to ring formation under the alkaline condition to obtain the pymetrozine.
An efficient protocol for the production of pymetrozine via a new synthetic strategy
Zhou, Qifan,Du, Fangyu,Shi, Yajie,Liu, Wenqiang,Liu, Dongdong,Chen, Guoliang
, p. 434 - 438 (2018/09/12)
A practical four-step synthesis of pymetrozine is reported, starting from a green chemical dimethyl carbonate and using the key intermediate methyl (E)-1-(2-oxopropyl)-2-(pyridin-3-ylmethylene)hydrazine-1-carboxylate. The main advantages of the route include inexpensive starting materials, environmental friendliness, short synthetic route, easy-to-use synthetic method and acceptable overall yield. A scale-up experiment was carried out to provide pymetrozine with 99.84% purity in 53.2% total yield.
A high-efficiency green pymetrozine preparation method
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Paragraph 0014; 0030; 0035; 0040-0042; 0043-0045; 0046-0048, (2017/08/25)
The invention discloses a high-efficiency and green method for preparing pymetrozine. According to the method, a byproduct methyl acetate produced in a pymetrozine condensation step serves as a raw material and replaces ethyl acetate in a traditional process for synthesizing acethydrazide, and the produced byproduct methanol can serve as a solvent in a subsequent step, so that the byproduct is recycled, and the raw material utilization rate is improved. Hydrogen chloride or concentrated hydrochloric acid in a traditional process is replaced by adopting a saturated hydrogen chloride methanol solution in the condensation step, and moisture in the system is avoided, so that amino triazone is subjected to a hydrolysis reaction, and byproducts are basically eliminated. According to the method, the yield of the product and the utilization rate of the hydrogen chloride are improved, the reaction time is shortened, emission of wastewater and waste gas is reduced, the comprehensive production cost is reduced, and better conditions are created for industrial large-scale production of the product.
Supramolecular water morphology and methanol solvate in a functionalized pymetrozine host
Wang,Xu,Cheng,Shao,Li
experimental part, p. 2541 - 2545 (2012/08/27)
The crystals of functionalized pymetrozine hydrochloride salts in water (crystal 1) and neutral pymetrozine in methanol (crystal 2) have been obtained. The carbonyl group and the nitrogen atom of Schiff base group of pymetrozine interact with hydrophilic groups (-OH) of methanol or water molecule to form one five-member ring via functional hydrogen bonds. Present results provide new insight and an understanding of the three-dimensional structural aspects of hydrogen bonded liquids with important implications in the structure and behaviour of functional molecules in biological systems.
Active agent combinations
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, (2008/06/13)
The novel active compound combinations of extracts from seeds of the neem tree and the active compounds of groups (B) to (F) listed in the description have very good insecticidal and acaricidal properties.
Process for the preparation of aminotriazine derivatives
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, (2008/06/13)
The present invention relates to a process for the preparation of aminotriazine derivatives of the formula I STR1 by the solvolysis of compounds of the formula II STR2 in the presence of gaseous hydrogen chloride in an alcoholic medium. The compounds of formula I are useful as intermediates in the manufacture of insecticides.