122846-17-7

Basic information

• Product Name: Glycine, N-acetyl-N-(4-methoxyphenyl)-, 1,1-dimethylethyl ester
• CAS NO: 122846-17-7
• Molecular Formula: C15H21NO4
• Molecular Weight: 279.336
• Mol File: 122846-17-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Glycine, N-acetyl-N-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-acetyl-N-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(122846-17-7)
• EPA Substance Registry System: Glycine, N-acetyl-N-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(122846-17-7)

Safety Data

• Hazardous Substances Data: 122846-17-7(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 75-36-5 acetyl chloride 
• 51-66-1 4-methoxyacetanilide 

Downstream Products

• 138924-38-6 3,4-trans-4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-3-(1-methylethenyl)-2-azetidinone 
• 138924-38-6 3,4-cis-4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-3-(1-methylethenyl)-2-azetidinone 
• 138924-35-3 3,4-cis-4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-3-(2,3-dimethylbutyl)-2-azetidinone 
• 138924-36-4 3,4-cis-4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-3-(2,3-dimethylbutyl)-2-azetidinone 
• 138924-34-2 3,4-cis-4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-3-(1-methylpentyl)-2-azetidinone 
• 122846-21-3 4-(tert-butoxycarbonyl)-1-(4-methoxyphenyl)-2-azetidinone 
• 138924-33-1 N-<(tert-butoxycarbonyl)methyl>-N-(4-methoxyphenyl)-2-butenamide 

Relevant articles and documents

Stereoselective Synthesis of β-Lactams by Oxidative Coupling of Dianions of Acyclic Tertiary Amides

Tertiary amides RCH2CON(R')CH2Z, where Z is an electron-withdrawing group, were converted into dianions by treatment with 2 equiv of n-butyllithium or tert-butyllithium, and the dianions were oxidized with N-iodoosuccinimide (NIS) or a Cu(II) carboxylate to form β-lactams stereoselectively.The stereochemistry of β-lactam formation depends on the oxidant; NIS is cis-selective, whereas Cu(II) is nonselective or slightly trans-selective.A high degree of asymmetric induction in the formation of β-lactams was achieved by using (R)-1-phenylethylamines a chiral auxiliary.This asymmetric ring closure was applied to the preparation of cis-β-lactam 31, an intermediate for the synthesis of the monobactam antibiotic carumonam.