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  • 1227926-70-6 Structure
  • Basic information

    1. Product Name: Phosphine oxide, [(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-
    2. Synonyms: Phosphine oxide, [(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-;[(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-phosphine oxide;(R)-(2,3-dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide
    3. CAS NO:1227926-70-6
    4. Molecular Formula: C24H37O2PSi
    5. Molecular Weight: 416.608641
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1227926-70-6.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Phosphine oxide, [(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Phosphine oxide, [(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-(1227926-70-6)
    11. EPA Substance Registry System: Phosphine oxide, [(2R)-2,3-diMethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-(1227926-70-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1227926-70-6(Hazardous Substances Data)

1227926-70-6 Usage

Description

Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-, is a complex organic compound with a unique molecular structure that features a phosphine oxide group attached to a diphenyl group. Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenylis characterized by its chiral center at the 2-position, which is designated as the R-configuration. The presence of two methyl groups and a triethylsilyl ether group further contributes to its distinct chemical properties.

Uses

Used in Pharmaceutical Industry:
Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-, is used as a reactant in the preparation of Paricalcitol, a pharmaceutical compound. Paricalcitol is a selective vitamin D receptor activator that is used to treat secondary hyperparathyroidism in patients with chronic kidney disease who are undergoing dialysis. The use of this phosphine oxide compound in the synthesis of Paricalcitol highlights its importance in the development of life-saving medications.

Check Digit Verification of cas no

The CAS Registry Mumber 1227926-70-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,9,2 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1227926-70:
(9*1)+(8*2)+(7*2)+(6*7)+(5*9)+(4*2)+(3*6)+(2*7)+(1*0)=166
166 % 10 = 6
So 1227926-70-6 is a valid CAS Registry Number.

1227926-70-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-(2,3-dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1227926-70-6 SDS

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