120686-09-1Relevant articles and documents
Synthesis method of 2-methoxy-7,8-dihydroquinoline-6(5H)-ketone
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Paragraph 0034-0036, (2018/03/26)
The invention relates to the technical field of chemical synthesis processes of tetrahydroquinoline derivatives, in particular to a synthesis method of 2-methoxy-7,8-dihydroquinoline-6(5H)-ketone. Inthe method, 1,4-cyclohexanedione monoethylene glycol is
A 2-methoxy-6-one -5, 6, 7, 8-tetrahydro-quinoline synthesis method
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, (2017/02/17)
The invention discloses a synthesis method of a drug intermediate 2-methoxy-6-one-5,6,7,8-tetrahydroquinoline. 1,4-cyclohexyldione monoethylene ketal used as the raw material is subjected to five-step reaction to generate the important intermediate 2-meth
Target-oriented multifunctional organocatalysis for enantioselective synthesis of bicyclo[3.3.1]nona-2,6-dien-9-ones. A formal asymmetric synthesis of huperzine A
Ding, Xiao-Hua,Li, Xiang,Liu, Dan,Cui, Wei-Chen,Ju, Xuan,Wang, Shaozhong,Yao, Zhu-Jun
experimental part, p. 6240 - 6248 (2012/08/28)
A target-oriented highly enantioselective multifunctional organocatalytic approach has been developed to construct the bicycle-[3.3.1]nona-2,6-dien-9-one core of (-)-huperzine A for the first time, with up to 95% ee in the gram-scale procedure. The newly established methodology is also eligible to synthesize a variety of bicyclo[3.3.1]nona-2,6-dien-9-ones in high enantiopurities, and thus is useful for the future development of novel huperzine A analogs with medicinal interests.