1204298-76-9 Usage
Description
6-(difluoromethyl)-2-mercaptopyrimidin-4-ol is a pyrimidine derivative chemical compound with the molecular formula C5H4F2N2OS. It features a difluoromethyl group at the carbon atom in position 6 and a mercapto group at the carbon atom in position 2, along with a hydroxyl group at the carbon atom in position 4. 6-(difluoromethyl)-2-mercaptopyrimidin-4-ol is utilized in pharmaceutical research and development as a potential drug candidate due to its unique structural features, which include the difluoromethyl and mercapto groups that may contribute to enhanced pharmacological properties.
Uses
Used in Pharmaceutical Research and Development:
6-(difluoromethyl)-2-mercaptopyrimidin-4-ol is used as a potential drug candidate for treating various diseases and conditions. Its unique molecular structure, including the difluoromethyl and mercapto groups, makes it a valuable building block for designing new drugs with improved pharmacological properties.
Used in Drug Design and Synthesis:
In the pharmaceutical industry, 6-(difluoromethyl)-2-mercaptopyrimidin-4-ol is used as a key intermediate in the synthesis of novel drug molecules. Its presence in drug candidates can potentially enhance their efficacy, selectivity, and pharmacokinetic profiles, leading to the development of more effective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1204298-76-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,2,9 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1204298-76:
(9*1)+(8*2)+(7*0)+(6*4)+(5*2)+(4*9)+(3*8)+(2*7)+(1*6)=139
139 % 10 = 9
So 1204298-76-9 is a valid CAS Registry Number.
1204298-76-9Relevant articles and documents
Design, synthesis, and acaricidal activity of phenyl methoxyacrylates containing 2-alkenylthiopyrimidine
Hao, Shulin,Cai, Zengfei,Cao, Yangyang,Du, Xiaohua
, (2020)
A series of novel phenyl methoxyacrylate derivatives containing a 2-alkenylthiopyrimidine substructure were designed, synthesized, and evaluated in terms of acaricidal activity. The structures of the title compounds were identified by 1H NMR, 13C NMR and high-resolution mass spectra (HRMS). Compound (E)-methyl 2-(2-((2-(3,3-dichloroallylthio)-6-(trifluoromethyl)pyrimidin-4-yloxy) methyl)phenyl)-3-methoxyacr-ylate (4j) exhibited significant acaricidal activity against Tetranychus cinnabarinus (T. cinnabarinus) in greenhouse tests possessing nearly twice the larvicidal and ovicidal activity compared to fluacrypyrim. Furthermore, the results of the field trials demonstrated that compound 4j could effectively control Panonychuscitri with long-lasting persistence and rapid action. The toxicology data in terms of LD50 value confirmed that compound 4j has a relatively low acute toxicity to mammals, birds, and honeybees.
