120298-37-5 Usage
Description
5,6-Dihydro-4H-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-sulphonamide, commonly known as DHTT, is an organic compound characterized by a thiopyran ring, which is a six-membered ring with one sulphur atom and five carbon atoms. Its structure also includes an additional sulphur atom bonded to an NH2 group, creating a sulfonamide. 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE is further distinguished by the presence of a hydroxyl (OH) and a methyl (CH3) group. Although DHTT itself is not widely recognized in mainstream research, its constituent parts, such as thiopyrans and sulphonamides, are significant in medicinal chemistry and are frequently utilized in drug development due to their bioactive properties.
Uses
Used in Pharmaceutical Industry:
5,6-Dihydro-4H-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-sulphonamide is used as a potential building block for new drug development for its bioactive properties. The presence of thiopyran and sulfonamide groups in its structure makes it a candidate for the synthesis of novel compounds with potential therapeutic applications.
Used in Medicinal Chemistry Research:
5,6-Dihydro-4H-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-sulphonamide is used as a research compound in medicinal chemistry to explore its potential interactions with biological targets. 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE's unique structure may offer insights into new mechanisms of action or lead to the discovery of new drugs with improved efficacy and safety profiles.
Used in Drug Synthesis:
5,6-Dihydro-4H-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-sulphonamide is used as an intermediate in the synthesis of more complex molecules with potential pharmaceutical applications. Its structural components can be modified or combined with other chemical entities to create new drugs with desired properties, such as increased potency, selectivity, or reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 120298-37-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,9 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 120298-37:
(8*1)+(7*2)+(6*0)+(5*2)+(4*9)+(3*8)+(2*3)+(1*7)=105
105 % 10 = 5
So 120298-37-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO3S3/c1-4-2-6(10)5-3-7(15(9,11)12)14-8(5)13-4/h3-4,6,10H,2H2,1H3,(H2,9,11,12)
120298-37-5Relevant articles and documents
Process for the preparation of 6-substituted-4-oxo-thieno [2,3b]thiopyran-2-sulfonic acid
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Page/Page column 6, (2008/12/04)
The present invention relates to one-pot process for the preparation of 6-substituted-4-oxo-thieno[2,3b]thiopyran-2-sulfonic acid of formula (I), which comprises, reacting 2-thienylthiol with alkenyl acid in the presence of an aromatic hydrocarbon solvent and a base, cyclization of the resulting compound and further reacting with an acid anhydride and sulfuric acid to get the desired compound of formula (I). The compound of formula (I) is the key intermediate in the preparation of (S,S)-5,6-dihydro-4-alkyylamino-6-substituted-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide and analogs thereof.
Process for preparing 5,6-dihydro-4-(S)-(ethylamino)-6-(S) methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide HCI
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Page/Page column 9, (2008/06/13)
The present invention relates to an improved process for the preparation of 5,6-dihydro-4-(S)-(ethylamino)-6-(S)methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide hydrochloride of formula (I) commonly known as Dorzolamide Hydrochloride useful as an agent to reduce intraoccular pressure by inhibiting carbonic anhydrase enzyme
Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
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, (2008/06/13)
Aromatic sulfonamides with a saturated heterocycle fused thereto are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.
