120-37-6 Usage
Description
3-Ethylamino-4-methylphenol is an organic compound characterized as a purple solid. It possesses unique chemical properties that make it suitable for various applications, particularly in the field of chemical synthesis.
Uses
Used in Chemical Synthesis:
3-Ethylamino-4-methylphenol is used as a key intermediate in the synthesis of complex organic compounds. Its chemical structure allows it to participate in various reactions, such as condensation reactions, which are crucial for creating new molecules with specific properties.
Used in Dye and Pigment Industry:
3-Ethylamino-4-methylphenol is used as a precursor in the production of rhodol, a type of dye. The compound undergoes a condensation reaction with 2-(2,4-dihydroxybenzoyl)benzoic acid to form rhodol, which is known for its vibrant color and is utilized in various applications, including the coloring of textiles, plastics, and other materials.
Used in Pharmaceutical Research:
Due to its unique chemical properties, 3-Ethylamino-4-methylphenol may also hold potential in the development of new pharmaceutical compounds. Its reactivity and structural features can be exploited to design and synthesize novel drug candidates with specific therapeutic applications.
Air & Water Reactions
3-Ethylamino-4-methylphenol may be sensitive to prolonged exposure to air. . Insoluble in water.
Reactivity Profile
An amine and phenol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
Fire Hazard
Flash point data for 3-Ethylamino-4-methylphenol are not available. 3-Ethylamino-4-methylphenol is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 120-37-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 120-37:
(5*1)+(4*2)+(3*0)+(2*3)+(1*7)=26
26 % 10 = 6
So 120-37-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO/c1-3-10-8-6-7(2)4-5-9(8)11/h4-6,10-11H,3H2,1-2H3
120-37-6Relevant articles and documents
Production process of alkaline red intermediate 3-ethylamino-p-methylphenol
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Paragraph 0060; 0065-0069, (2021/03/31)
The invention relates to a production process of an alkaline red intermediate 3-ethylamino p-methylphenol. The production process specifically comprises the following steps: step 1, an alkylation reaction: carrying out alkylation reaction on o-toluidine and absolute ethyl alcohol under the action of a catalyst magnetic solid acid to generate an alkylate mixture; and then rectifying the alkylate mixture to obtain the N-ethyl o-toluidine; wherein the reaction temperature of the alkylation reaction is 60-120 DEG C; wherein the addition amount of the magnetic solid acid is 4-6% of the mass ratio of the feed liquid; step 2, a sulfonation reaction: carrying out sulfonation reaction on the N-ethyl o-toluidine and fuming sulfuric acid to generate 3ethylamino-p-toluenesulfonic acid; step 3, a hydroxylation reaction: carrying out hydroxylation reaction on 3ethylamino p-toluenesulfonic acid and potassium hydroxide to generate 3-ethylamino p-methylphenol potassium salt; and step 4, acid precipitation: reacting the 3-ethylamino p-methylphenol potassium salt with hydrochloric acid to prepare the 3-ethylamino p-methylphenol. The production process is high in yield and short in reaction time.
