119577-28-5 Usage
Description
7-Ethyl-10-hydroxycamptothecin, also known as SN-38, is a potent derivative of camptothecin, a quinoline alkaloid native to the tree Camptotheca acuminata. With a 98% purity level, it is a highly effective cytotoxic agent against a range of cancer types. SN-38 acts by inhibiting the DNA enzyme Topoisomerase I, thus preventing cancer cell replication and promoting programmed cell death (apoptosis).
Uses
Used in Oncology:
7-ETHYL-10-HYDROXYCAMPTOTHECIN,98% is used as an antitumor agent for its ability to inhibit the DNA enzyme Topoisomerase I, preventing cancer cell replication and promoting apoptosis.
Used in Chemotherapy:
7-ETHYL-10-HYDROXYCAMPTOTHECIN,98% is used as the active metabolite of the prodrug Irinotecan, a commonly used chemotherapeutic medication, making it a crucial component in cancer treatment protocols.
Used in Cancer Research:
7-ETHYL-10-HYDROXYCAMPTOTHECIN,98% is used as a research compound for studying the mechanisms of action and potential applications in the development of new anticancer therapies, given its potent cytotoxic properties and effectiveness against various cancer types.
Check Digit Verification of cas no
The CAS Registry Mumber 119577-28-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,5,7 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 119577-28:
(8*1)+(7*1)+(6*9)+(5*5)+(4*7)+(3*7)+(2*2)+(1*8)=155
155 % 10 = 5
So 119577-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H16N2O5/c1-2-20(26)13-7-15-17-10(6-11-14(21-17)4-3-5-16(11)23)8-22(15)18(24)12(13)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
