119060-47-8

Basic information

• Product Name: tert-Butyl 2,2-dichlorocyclopropanecarboxylate
• Synonyms: tert-Butyl 2,2-dichlorocyclopropanecarboxylate
• CAS NO: 119060-47-8
• Molecular Weight: 211.088
• Mol File: 119060-47-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-Butyl 2,2-dichlorocyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 2,2-dichlorocyclopropanecarboxylate(119060-47-8)
• EPA Substance Registry System: tert-Butyl 2,2-dichlorocyclopropanecarboxylate(119060-47-8)

Safety Data

• Hazardous Substances Data: 119060-47-8(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 1663-39-4 tert-Butyl acrylate 

Downstream Products

• 119060-44-5 tert-Butyl 4,4,5,5-tetrachlorospiropentanecarboxylate 
• 119060-62-7 2,2-Bis-(cyano-diphenyl-methyl)-cyclopropanecarboxylic acid tert-butyl ester 
• 89723-51-3 trans-(2-Chlorocyclopropyl)carbinol 
• 5365-23-1 2,2-dichloro-1-hydroxymethyl-cyclopropane 
• 119060-42-3 2,2-Diphenoxy-cyclopropanecarboxylic acid tert-butyl ester 
• 119060-61-6 2,2-Bis-(cyano-methyl-phenyl-methyl)-cyclopropanecarboxylic acid tert-butyl ester 
• 119060-43-4 2,2-Bis-phenylsulfanyl-cyclopropanecarboxylic acid tert-butyl ester 
• 14734-25-9 succinic acid (methyl)(tert-butyl)diester 

Relevant articles and documents

Reactions of Organic Anions; CXLIX. Reactions of gem-Dichlorocyclopropanes Containing an Electron-Withdrawing Substituent with Organic Anions Generated with Phase-Transfer Catalysis

gem-Dichlorocyclopropanes 1 react with C-H, O-H and S-H acids in the presence of concentrated sodium hydroxide solution and a phase-transfer catalyst to give gem-disubstituted cyclopropanes 2 or chain products 3 in 44-95percent yield.

Catalyst Effects on Reactions of α,β-Unsaturated Ketones and Esters with Haloforms under Phase-Transfer Catalysis

Reactions of acceptor-substituted alkenes with haloform/sodium hydroxide and PT-catalyst result in dihalocarbene additions competitive to Michael additions, with or without consecutive cyclization, and further reactions.Product compositions are strongly dependent on the nature of the phase-transfer catalyst: Sterically unhindered quarternary ammonium ions and benzo-crown ethers favour processes via carbenes, large delocalized (soft) cations foster primary Michael additions.Thus, tert-butyl cis-crotonate is dichlorocyclopropanated stereospecifically with NMe4Cl.The respective stereospecific CBr2 conversion is successful only with PhHgCBr3 .