1176788-84-3Relevant articles and documents
Structure-guided development of selective TbcatB inhibitors
Mallari, Jeremy P.,Shelat, Anang A.,Kosinski, Aaron,Caffrey, Conor R.,Connelly, Michele,Zhu, Fangyi,McKerrow, James H.,Kiplin Guy
, p. 6489 - 6493 (2009)
The trypanosomal cathepsin TbcatB is essential for parasite survival and is an attractive therapeutic target. Herein we report the structure-guided development of TbcatB inhibitors with specificity relative to rhodesain and human cathepsins B and L. Inhib
