116538-95-5 Usage
Description
Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is a heterocyclic chemical compound with the molecular formula C8H4N2S. It features a unique structure that includes both sulfur and nitrogen atoms, which endows it with distinctive reactivity and properties. Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is widely recognized for its potential in medicinal chemistry and drug development, particularly as a starting material for synthesizing bioactive molecules. Its molecular structure and reactivity make it a valuable asset in the creation of new compounds with possible therapeutic applications.
Uses
Used in Organic Synthesis:
Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is utilized as a building block in organic synthesis for its unique reactivity and properties. It serves as a key component in the creation of various complex organic molecules.
Used in Drug Discovery:
In the field of drug discovery, Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is employed as a starting material for the synthesis of bioactive molecules. Its potential pharmacological and biological activities make it a promising candidate for developing new therapeutic agents.
Used in Medicinal Chemistry:
Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is of interest in medicinal chemistry due to its potential as a precursor for the development of compounds with therapeutic applications. Its molecular structure allows for the design and synthesis of novel molecules that can target specific biological pathways or receptors.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, Thieno[3,2-b]pyridine-6-carbonitrile (9CI) is used as a key intermediate in the production of various pharmaceuticals. Its unique properties and reactivity contribute to the development of innovative drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 116538-95-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,5,3 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 116538-95:
(8*1)+(7*1)+(6*6)+(5*5)+(4*3)+(3*8)+(2*9)+(1*5)=135
135 % 10 = 5
So 116538-95-5 is a valid CAS Registry Number.
116538-95-5Relevant articles and documents
Efficient Route for the Synthesis of Diverse Heteroannelated 5-Cyanopyridines
Mityuk, Andrey P.,Hrebonkin, Andrii,Lebed, Pavlo S.,Grabchuk, Galyna P.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.
, p. 2133 - 2141 (2021/02/22)
The new efficient, convenient protocol for the synthesis of heteroannelated 3-cyanopyridines and pyrimidines starting from diverse aminoheterocycles and 3,3-dimethoxy-2-formylpropionitrile sodium salt was elaborated. The advantages and improvements of the
BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY
-
Page/Page column 110, (2017/07/14)
A compound of formula (Ia) or (Ib) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of a histone deacetylase, and as such is useful in terepy, e.g. in the treatment of autoimmune disorders, mental disorders, neurodegenerative disorders, and hyperproliferative disorders.
α-vinylation of β-aminothiophene derivatives. Synthesis of 6- functionalized thieno[3,2-b]pyridines
Berkaoui, M'hamed,Outurquin, Francis,Paulmier, Claude
, p. 9055 - 9066 (2007/10/03)
The acid-catalyzed reductive α-alkylation of β-aminothiophenes was applied to the N-(thien-3-yl)acetamide and alkyl N-(thien-3-yl)carbamates. Without reduction, β-amino α-vinylthiophenes were obtained when α-branched aldehydes were used. β-(3-Aminothien-2-yl)α,β-unsaturated ketones, esters and nitriles were also prepared from the corresponding α-functionalized acetals. These amines are intermediates in the formation of thieno[3,2- b]pyridines bearing a functional group at the β-position of the pyridine ring.
