115822-58-7

Basic information

• Product Name: CHROMAN-3-CARBONYL CHLORIDE
• Synonyms: CHROMAN-3-CARBONYL CHLORIDE;Chromane-3-carbonylchloride;chroman-3-carboyl chloride;2H-1-Benzopyran-3-carbonylchloride,3,4-dihydro-(9CI)
• CAS NO: 115822-58-7
• Molecular Formula: C₁₀H₉ClO₂
• Molecular Weight: 196.63
• Product Categories: ACIDHALIDE
• Mol File: 115822-58-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 292.4 °C at 760 mmHg
• Flash Point: 108.9 °C
• Appearance: /
• Density: 1.281 g/cm³
• Vapor Pressure: 0.00184mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: CHROMAN-3-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CHROMAN-3-CARBONYL CHLORIDE(115822-58-7)
• EPA Substance Registry System: CHROMAN-3-CARBONYL CHLORIDE(115822-58-7)

Safety Data

• Hazardous Substances Data: 115822-58-7(Hazardous Substances Data)

Usage

General Description

CHROMAN-3-CARBONYL CHLORIDE is a chemical compound with the molecular formula C9H7ClO2. It is a chlorinated derivative of chroman-3-carbonyl, which is a heterocyclic compound with a chroman ring and a carbonyl group. CHROMAN-3-CARBONYL CHLORIDE is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is a highly reactive and versatile compound that can undergo various chemical reactions, such as nucleophilic substitution and acylation. CHROMAN-3-CARBONYL CHLORIDE is also used as an intermediate in the production of dyes and pigments, as well as in the development of new materials and chemical processes. However, it should be handled with care due to its corrosive and irritant properties.

InChI:InChI=1/C10H9ClO2/c11-10(12)8-5-7-3-1-2-4-9(7)13-6-8/h1-4,8H,5-6H2

Upstream product

• 90-02-8 salicylaldehyde 
• 22649-28-1 2H-chromene-3-carboxylic acid 
• 57543-66-5 2H-chromene-3-carbonitrile 
• 115822-57-6 3,4-dihydro-2H-1-benzopyran-3-carboxylic acid 

Downstream Products

• 1202252-04-7 C₂₄H₂₂BrNO₃S 
• 1213262-89-5 C₂₅H₂₄BrNO₄S 
• 1213262-80-6 C₂₈H₃₁BrN₂O₄S 

Relevant articles and documents

NEW COMPOUNDS AND THEIR USE AS THERAPEUTICALLY ACTIVE SUBSTANCES IN THE TREATMENT AND/OR PREVENTION OF DISEASES INVOLVING THE RETINAL PIGMENT EPITHELIUM

The present invention relates to new compounds and to their use as therapeutically active substances in the treatment and/or prevention of diseases involving the retinal pigment epithelium, and in particular in the treatment and/or prevention of diseases

Regio- and stereoselective Pd-catalyzed direct arylation of unactivated sp3 C(3)-H bonds of tetrahydrofuran and 1,4-benzodioxane systems

An auxiliary-enabled Pd-catalyzed highly regio- and stereoselective sp3 C-H activation and the direct arylation of the C3-position of oxygen heterocycles, such as tetrahydrofuran and 1,4-benzodioxane systems, are reported. An efficient stereoselective construction of cis 2,3-disubstituted tetrahydrofuran derivatives (analogues of norlignans) and cis 2,3-disubstituted 1,4-benzodioxane derivatives (analogues of neolignans) is described. The direct C(sp3)-H arylation of the C3-position of (R)- or (S)- tetrahydrofuran-2-carboxamides furnished the corresponding (2R,3R) and (2S,3S) C3-arylated THF scaffolds as major compounds with very high regio- and diastereoselectivities. The stereochemistry of the products obtained in this work were unambiguously assigned on the basis of the X-ray structure analyses of representative compounds 3b, 3e, 4p, and 7.