115467-07-7

Basic information

• Product Name: 3,5-Difluoro-4-(trifluoromethoxy)bromobenzene
• Synonyms: 3,5-Difluoro-4-(trifluoromethoxy)bromobenzene;4-BroMo-2,6-difluoro(trifluoroMethoxy)benzene;5-Bromo-1,3-difluoro-2-(trifluoromethoxy)benzene;2,6-Difluoro-4-bromotrifluoromethoxybenzene;4-Bromo-2,6-fluorotrifluoromethoxybenzene
• CAS NO: 115467-07-7
• Molecular Formula: C7H2BrF5O
• Molecular Weight: 276.986196
• Mol File: 115467-07-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 175.315oC at 760 mmHg
• Flash Point: 72.901oC
• Appearance: /
• Density: 1.794g/cm3
• Vapor Pressure: 1.55mmHg at 25°C
• Refractive Index: 1.4330 to 1.4370
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,5-Difluoro-4-(trifluoromethoxy)bromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Difluoro-4-(trifluoromethoxy)bromobenzene(115467-07-7)
• EPA Substance Registry System: 3,5-Difluoro-4-(trifluoromethoxy)bromobenzene(115467-07-7)

Safety Data

• Hazardous Substances Data: 115467-07-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless transparent liquid

InChI:InChI=1/C7H2BrF5O/c8-3-1-4(9)6(5(10)2-3)14-7(11,12)13/h1-2H

Upstream product

• 104197-13-9 4-bromo-2,6-difluorophenol 

Downstream Products

• 195206-85-0 3,5-difluoro-4-(trifluoromethoxy)phenol 

Relevant articles and documents

A 4 - bromo - 2, 6 - two fluorine three fluorine methoxybenzene preparation method

The invention relates to the field of organic synthesis, particularly a preparation method of 4-bromo-2, 6-difluorotrifluoromethoxybenzene. The preparation method of 4-bromo-2, 6-difluorotrifluoromethoxybenzene provided by the invention comprises the following steps: (1) esterification reaction: reacting 4-bromo-2, 6-difluorophenol with an esterification reagent in the presence of an alkali in a reaction solvent to generate 4-bromo-2, 6-difluoro-difluorobromomethoxybenzene or 4-bromo-2, 6-difluoro-difluorochloromethoxybenzene; and (2) fluoridation reaction: reacting the product obtained in the step (1) with a fluoridation reagent under the action of a catalyst to generate 4-bromo-2, 6-difluorotrifluoromethoxybenzene. The preparation method of 4-bromo-2, 6-difluorotrifluoromethoxybenzene, provided by the invention, is simple in process and mild in reaction condition, can be carried out at a normal pressure, and is suitable for industrial production.