1140502-22-2

Basic information

• Product Name: 5-{5-[2-(piperazin-1-yl)pyrimidin-5-yl]-1H-benzimidazol-1-yl}-3-({(1R)-1-[2-chlorophenyl]ethyl}oxy)thiophene-2-carboxamide
• Synonyms: 5-{5-[2-(piperazin-1-yl)pyrimidin-5-yl]-1H-benzimidazol-1-yl}-3-({(1R)-1-[2-chlorophenyl]ethyl}oxy)thiophene-2-carboxamide
• CAS NO: 1140502-22-2
• Molecular Weight: 560.079
• Mol File: 1140502-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-{5-[2-(piperazin-1-yl)pyrimidin-5-yl]-1H-benzimidazol-1-yl}-3-({(1R)-1-[2-chlorophenyl]ethyl}oxy)thiophene-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{5-[2-(piperazin-1-yl)pyrimidin-5-yl]-1H-benzimidazol-1-yl}-3-({(1R)-1-[2-chlorophenyl]ethyl}oxy)thiophene-2-carboxamide(1140502-22-2)
• EPA Substance Registry System: 5-{5-[2-(piperazin-1-yl)pyrimidin-5-yl]-1H-benzimidazol-1-yl}-3-({(1R)-1-[2-chlorophenyl]ethyl}oxy)thiophene-2-carboxamide(1140502-22-2)

Safety Data

• Hazardous Substances Data: 1140502-22-2(Hazardous Substances Data)

Upstream product

• 929278-56-8 3-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-5-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazol-1-yl]-2-thiophenecarboxamide 
• 99931-82-5 1-(5-bromopyrimidin-2-yl)piperazine 

Relevant articles and documents

Convenient synthesis of heteroaryl-linked benzimidazoles via microwave-assisted boronate ester formation

N-Substituted 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazoles were conveniently accessed via microwave-assisted synthesis. Subsequent Suzuki-Miyaura cross-coupling with heteroaryl halides proceeded to give a wide variety of heteroaryl-su