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  • 112-00-5 Structure
  • Basic information

    1. Product Name: Dodecyltrimethylammonium chloride
    2. Synonyms: LTAC;LAURYLTRIMETHYLAMMONIUM CHLORIDE;IPC-DTMA-CL;DODECYLTRIMETHYLAMMONIUM CHLORIDE;DTAC;N-DODECYLTRIMETHYLAMMONIUM CHLORIDE;N,N,N-Trimethyl-1-dodecanaminium chloride;TRIMETHYLDODECYLAMMONIUM CHLORIDE
    3. CAS NO:112-00-5
    4. Molecular Formula: C15H34N*Cl
    5. Molecular Weight: 263.89
    6. EINECS: 203-931-2
    7. Product Categories: Quaternary ammonium salt;Alkylamine Salts & Quarternary Ammonium Salts (Surfactants);Ammonium Chlorides (Quaternary);Cationic Surfactants;Functional Materials;Quaternary Ammonium Compounds;Surfactants;Analytical Chemistry;HPLC Ion-Pair Reagents for Acidic Samples;Ion-Pair Reagents for HPLC;Water Ttreatment Chemicals;Ammonium Salts;Greener Alternatives: Catalysis;Phase Transfer Catalysts;Aliphatics;Amines
    8. Mol File: 112-00-5.mol
    9. Article Data: 4
  • Chemical Properties

    1. Melting Point: 246 °C (dec.)(lit.)
    2. Boiling Point: 412.12°C (rough estimate)
    3. Flash Point: 19 °C
    4. Appearance: White to light yellow/Powder or Chunks
    5. Density: 0.9265 (rough estimate)
    6. Vapor Pressure: 0Pa at 25℃
    7. Refractive Index: n20/D 1.426
    8. Storage Temp.: Store below +30°C.
    9. Solubility: H2O: 50 mg/mL, clear, colorless
    10. Water Solubility: Soluble
    11. Sensitive: Hygroscopic
    12. Stability: Stable. Incompatible with strong oxidizing agents. Protect from moisture.
    13. BRN: 3915951
    14. CAS DataBase Reference: Dodecyltrimethylammonium chloride(CAS DataBase Reference)
    15. NIST Chemistry Reference: Dodecyltrimethylammonium chloride(112-00-5)
    16. EPA Substance Registry System: Dodecyltrimethylammonium chloride(112-00-5)
  • Safety Data

    1. Hazard Codes: Xi,N,Xn,F
    2. Statements: 36/37/38-50-50/53-22-67-11
    3. Safety Statements: 26-61-60-37/39-36-16
    4. RIDADR: UN 3077 9/PG 3
    5. WGK Germany: 3
    6. RTECS: JR2122500
    7. F: 3-10
    8. TSCA: Yes
    9. HazardClass: 6.1(b)
    10. PackingGroup: III
    11. Hazardous Substances Data: 112-00-5(Hazardous Substances Data)

112-00-5 Usage

Description

Dodecyltrimethylammonium chloride is a cationic alkyltrimethylammonium chloride surfactant that can undergo micellization in aqueous solution. It is a white solid and is mainly used for the denaturation of proteins.

Uses

1. Used in Paint Stripping:
Dodecyltrimethylammonium chloride is used as a paint stripper for its ability to break down and remove paint from various surfaces.
2. Used in Foam Stabilization:
It is used as a foaming stabilizer in the production of foams, enhancing their stability and performance.
3. Used in Bactericidal Lotions:
Dodecyltrimethylammonium chloride is used as a bactericidal agent in lotions, providing antimicrobial properties.
4. Used in Coating, Plastics, and Paints Production:
Dodecyltrimethylammonium chloride is used as an anti-static agent and catalyst in the production of coatings, plastics, and paints, improving their processing and performance.
5. Used in Rubber and Ink Production:
It is also utilized in the rubber and ink industries as an anti-static agent and catalyst, enhancing the manufacturing process and product quality.

Purification Methods

Dissolve the chloride in MeOH, treat with active charcoal, filter and dry it in vacuo [Waldenburg J Phys Chem 88 1655 1984], or recrystallise it several times from 10% EtOH in acetone. It has also been repeatedly crystallised from EtOH/ether or MeOH. [Cella et al. J Am Chem Soc 74 2062 1952, Beilstein 4 IV 79.]

Check Digit Verification of cas no

The CAS Registry Mumber 112-00-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 112-00:
(5*1)+(4*1)+(3*2)+(2*0)+(1*0)=15
15 % 10 = 5
So 112-00-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H34N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1

112-00-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A17924)  (1-Dodecyl)trimethylammonium chloride, 97%   

  • 112-00-5

  • 5g

  • 467.0CNY

  • Detail
  • Alfa Aesar

  • (A17924)  (1-Dodecyl)trimethylammonium chloride, 97%   

  • 112-00-5

  • 25g

  • 1111.0CNY

  • Detail
  • Alfa Aesar

  • (A17924)  (1-Dodecyl)trimethylammonium chloride, 97%   

  • 112-00-5

  • 100g

  • 3788.0CNY

  • Detail
  • Aldrich

  • (44242)  Dodecyltrimethylammoniumchloride  ≥99.0% (AT)

  • 112-00-5

  • 44242-25G

  • 802.62CNY

  • Detail
  • Aldrich

  • (44242)  Dodecyltrimethylammoniumchloride  ≥99.0% (AT)

  • 112-00-5

  • 44242-100G

  • 2,576.34CNY

  • Detail
  • Sigma-Aldrich

  • (17104)  Dodecyltrimethylammoniumchloride  purum, ≥98.0% (AT)

  • 112-00-5

  • 17104-25G

  • 1,359.54CNY

  • Detail
  • Sigma-Aldrich

  • (17104)  Dodecyltrimethylammoniumchloride  purum, ≥98.0% (AT)

  • 112-00-5

  • 17104-100G

  • 3,993.21CNY

  • Detail

112-00-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name Dodecyl trimethyl ammonium chloride

1.2 Other means of identification

Product number -
Other names Dodecyltrimethylammonium chloride (DTAC)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Processing aids, not otherwise listed,Surface active agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112-00-5 SDS

112-00-5Synthetic route

1-chlorododecane
112-52-7

1-chlorododecane

trimethylamine
75-50-3

trimethylamine

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Conditions
ConditionsYield
In methanol; ethanol for 24h; Heating;49%
With ethanol at 80 - 90℃;
With water at 80℃;
methylene chloride
74-87-3

methylene chloride

N,N-dimethylaminododecane
112-18-5

N,N-dimethylaminododecane

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Conditions
ConditionsYield
With pentane at 60℃;
ethanol
64-17-5

ethanol

1-chlorododecane
112-52-7

1-chlorododecane

trimethylamine
75-50-3

trimethylamine

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Conditions
ConditionsYield
analoge Reaktionen mit hoeheren Alkylhalogeniden;
C29H38N6O4*C15H34N(1+)*Cl(1-)

C29H38N6O4*C15H34N(1+)*Cl(1-)

A

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

B

Trp-Aib-Gly-Leu-NHPh
232279-44-6

Trp-Aib-Gly-Leu-NHPh

Conditions
ConditionsYield
In chloroform-d1 at 24.84℃; Equilibrium constant; complex formation;
C31H42N6O4*C15H34N(1+)*Cl(1-)

C31H42N6O4*C15H34N(1+)*Cl(1-)

A

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

B

Trp-Aib-Gly-Leu-NH-C6H3(3,5-Me2)
271770-12-8

Trp-Aib-Gly-Leu-NH-C6H3(3,5-Me2)

Conditions
ConditionsYield
In chloroform-d1 at 24.84℃; Equilibrium constant; complex formation;
dodecylammonium chloride
929-73-7

dodecylammonium chloride

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Conditions
ConditionsYield
With 1-ethyl-3-methylimidazolium bromide at 169.84℃; for 8h;
n-Dodecylamine
124-22-1

n-Dodecylamine

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous ethanol / 60 - 80 °C
2: skellysolve-A / 60 °C
View Scheme
α,α-dichloro-m-xylene
2719-42-8

α,α-dichloro-m-xylene

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

3-Methylbenzotrichloride
3335-34-0

3-Methylbenzotrichloride

Conditions
ConditionsYield
With sodium hydroxide In tetrachloromethane; water93.4%
sodium tetraphenyl borate
143-66-8

sodium tetraphenyl borate

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

dodecyltrimethylammonium tetraphenylborate

dodecyltrimethylammonium tetraphenylborate

Conditions
ConditionsYield
In water at 85℃; for 1.16667h;92%
potassium tetrachloroaurate(III) dihydrate

potassium tetrachloroaurate(III) dihydrate

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

1-dodecylthiol
112-55-0

1-dodecylthiol

[lauryltrimethylammonium][Au(dodecanethiolate)2]
349490-82-0

[lauryltrimethylammonium][Au(dodecanethiolate)2]

Conditions
ConditionsYield
With sodium methylate In methanol ammonium halide mixed with Au compd. (1:1), suspn. of ammonium chloroaurate treated with thiol (4 equiv.) and NaOMe (4 equiv.); pptd., filtered off, washed (water, MeOH), dried (vac.), elem. anal.;91%
chloroamine-T
127-65-1

chloroamine-T

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

C15H34N(1+)*C7H7ClNO2S(1-)

C15H34N(1+)*C7H7ClNO2S(1-)

Conditions
ConditionsYield
In water at 5℃; for 5h;86%
hexachloroethane
67-72-1

hexachloroethane

3-Methylbenzotrichloride
3335-34-0

3-Methylbenzotrichloride

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

α,α,α,α'-tetrachloro-m-xylene

α,α,α,α'-tetrachloro-m-xylene

Conditions
ConditionsYield
With potassium hydroxide In 1,1,2,2-tetrachloroethylene; water85.2%
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

epichlorohydrin
106-89-8

epichlorohydrin

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol
100-79-8

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

2,2-dimethyl-4-(2',3'-epoxy) propoxymethyl-1,3-dioxolane

2,2-dimethyl-4-(2',3'-epoxy) propoxymethyl-1,3-dioxolane

Conditions
ConditionsYield
With potassium hydroxide In hexane78%
acetone glycerol ketal

acetone glycerol ketal

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

epichlorohydrin
106-89-8

epichlorohydrin

2,2-dimethyl-4-(2',3'-epoxy) propoxymethyl-1,3-dioxolane

2,2-dimethyl-4-(2',3'-epoxy) propoxymethyl-1,3-dioxolane

Conditions
ConditionsYield
With sodium hydroxide In hexane78%
copper (11) chloride dihydrate

copper (11) chloride dihydrate

tris (triphenylphosphine) ruthenium (11) chloride

tris (triphenylphosphine) ruthenium (11) chloride

1-Decene
872-05-9

1-Decene

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Decan-2-one
693-54-9

Decan-2-one

Conditions
ConditionsYield
In water; ethyl acetate; benzene64%
CH(COC4H3NC6H2(O(CH2)15CH3)3)2BF2

CH(COC4H3NC6H2(O(CH2)15CH3)3)2BF2

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

C15H34N(1+)*C119H209BClF2N2O8(1-)

C15H34N(1+)*C119H209BClF2N2O8(1-)

Conditions
ConditionsYield
In 1,4-dioxane Heating;63%
pentacyanocyclopentadienyl anion sodium salt

pentacyanocyclopentadienyl anion sodium salt

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

C10N5(1-)*C15H34N(1+)

C10N5(1-)*C15H34N(1+)

Conditions
ConditionsYield
In water for 0.166667h;39%
copper(II) chloride dihydrate

copper(II) chloride dihydrate

1-Decene
872-05-9

1-Decene

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

palladium dichloride

palladium dichloride

Decan-2-one
693-54-9

Decan-2-one

Conditions
ConditionsYield
In water; ethyl acetate; benzene2%
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Trp-Aib-Gly-Leu-NHPh
232279-44-6

Trp-Aib-Gly-Leu-NHPh

C29H38N6O4*C15H34N(1+)*Cl(1-)

C29H38N6O4*C15H34N(1+)*Cl(1-)

Conditions
ConditionsYield
In chloroform-d1 at 24.84℃; Equilibrium constant; complex formation;
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

Trp-Aib-Gly-Leu-NH-C6H3(3,5-Me2)
271770-12-8

Trp-Aib-Gly-Leu-NH-C6H3(3,5-Me2)

C31H42N6O4*C15H34N(1+)*Cl(1-)

C31H42N6O4*C15H34N(1+)*Cl(1-)

Conditions
ConditionsYield
In chloroform-d1 at 24.84℃; Equilibrium constant; complex formation;
C18H12N2O5S
953077-73-1

C18H12N2O5S

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

C15H34N(1+)*C18H11N2O5S(1-)

C15H34N(1+)*C18H11N2O5S(1-)

Conditions
ConditionsYield
In water; isopropyl alcohol at 80℃; for 2h;
C42H82O17

C42H82O17

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

C15H34N(1+)*C42H81O17(1-)

C15H34N(1+)*C42H81O17(1-)

Conditions
ConditionsYield
With potassium hydroxide In water pH=7;
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

3-Methyl-2-nitrobenzal chloride
99318-68-0

3-Methyl-2-nitrobenzal chloride

2-nitro-3-methyl benzyl chloride
70018-11-0

2-nitro-3-methyl benzyl chloride

3-Methyl-2-nitrobenzotrichloride
99318-66-8

3-Methyl-2-nitrobenzotrichloride

Conditions
ConditionsYield
With sodium hydroxide In tetrachloromethane; dichloromethane; tert-butyl alcohol
3-bromomethylthiophene-2-sulfonamide
111283-83-1

3-bromomethylthiophene-2-sulfonamide

2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

3-(2,2,2-trifluoroethoxymethyl)-2-thiophenesulfonamide

3-(2,2,2-trifluoroethoxymethyl)-2-thiophenesulfonamide

Conditions
ConditionsYield
With sodium hydroxide In water
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

dodecyltrimethylammonium tetracarbonylcobaltate

dodecyltrimethylammonium tetracarbonylcobaltate

Conditions
ConditionsYield
In sodium hydroxide; toluene the Co-compd. and the chloride are dissolved in a degassed mixt. of 5 MNaOH and toluene under CO, stirring of the soln. for 40 min; removal of the org. phase (syringe) and drying (MgSO4) under CO;
lithium cobalt(III) oxide

lithium cobalt(III) oxide

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

[C12H25N(CH3)3]0.4Li0.4CoO2

[C12H25N(CH3)3]0.4Li0.4CoO2

[(DPPE)((C6H5)2P(CH2)2P(C6H5)(C6H4))Ru](PF6)
199533-73-8

[(DPPE)((C6H5)2P(CH2)2P(C6H5)(C6H4))Ru](PF6)

trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

(DPPE)((C6H5)2PCH2CH2P(C6H5)(C6H4))RuCl

(DPPE)((C6H5)2PCH2CH2P(C6H5)(C6H4))RuCl

Conditions
ConditionsYield
In dichloromethane-d2 room temp.;
trimethyldodecylammonium chloride
112-00-5

trimethyldodecylammonium chloride

dermatan sulfate

dermatan sulfate

dermatan sulfate dodecyltrimethylammonium salt

dermatan sulfate dodecyltrimethylammonium salt

Conditions
ConditionsYield
In water

112-00-5Related news

Micellar behavior of dodecyldimethylethyl ammonium bromide and Dodecyltrimethylammonium chloride (cas 112-00-5) in aqueous media in the presence of diclofenac sodium08/27/2019

The micellar properties of cationic surfactants (S) viz. dodecyldimethylethyl ammonium bromide (DDAB) and dodecyltrimethylammonium chloride (DTAC) in aqueous media in the presence of diclofenac sodium (D) have been investigated by spectroscopic and conductivity measurements. The UV–vis and 1H N...detailed

Effect of temperature on critical micelle concentration and thermodynamic behavior of dodecyldimethylethylammonium bromide and Dodecyltrimethylammonium chloride (cas 112-00-5) in aqueous media08/26/2019

Micellar behavior of cationic surfactants, dodecyldimethylethylammonium bromide (DDAB) and dodecyltrimethylammonium chloride (DTAC) in aqueous media has been investigated over the temperature range 288.15–308.15 K. The critical micelle concentration (cmc) and degree of ionization (β) of the mi...detailed

Facile synthesis and morphology control of highly ordered cubic mesoporous silica SBA-1 using short chain Dodecyltrimethylammonium chloride (cas 112-00-5) as the structure-directing agent08/25/2019

We presented a facile synthesis route for the formation of highly ordered cubic mesoporous silicas SBA-1 (Pm3n mesophase) with rich morphologies over a broad synthesis temperature range and synthesis compositions by using dodecyltrimethylammonium chloride (C12TMACl), a surfactant with a relative...detailed

Temperature and salt-induced micellization of Dodecyltrimethylammonium chloride (cas 112-00-5) in aqueous solution: A thermodynamic study08/23/2019

Thermodynamics of micelle formation of the cationic surfactant dodecyltrimethylammonium chloride (DTAC) in water and aqueous NaCl solutions were investigated. Isothermal titration calorimetry (ITC) has been used to study the effect of the added NaCl on the critical micelle concentration, cmc, an...detailed

Hydrophobicity of counterions as a driving force in the self-assembly process: Dodecyltrimethylammonium chloride (cas 112-00-5) and parabens08/22/2019

The micelle formation of dodecyltrimethylammonium chloride (DTAC) in 0.01 M methyl- and ethyl-4-hydroxybenzoate (MeP and EtP, respectively) sodium salt aqueous solutions has been investigated at several temperatures in the range from 278.15 to 328.15 K by isothermal titration calorimetry, viscos...detailed

Short communicationDevelopment and characterization of nanocapsules comprising Dodecyltrimethylammonium chloride (cas 112-00-5) and κ-carrageenan08/21/2019

The aim of this work was to develop and characterize a new type of nanocapsules. To this end, a nanoemulsion bearing an oily core (Miglyol 812) was obtained by spontaneous emulsification and stabilized by dodecyl-trimethylammonium chloride (DTAC), a commercial cationic surfactant; this nanoemuls...detailed

Molecular dynamics study of stability and disintegration of long rod-like micelles: Dodecyltrimethylammonium chloride (cas 112-00-5) in solutions of hydroxybenzoates*08/20/2019

Recently it was found out that different positions of the hydroxylic group on hydroxybenzoate anions (HB) crucially affect the thermodynamics of the self-organization of the cationic surfactant dodecyltrimethylammonium chloride (DTAC) and also the structure of resulting aggregates. In our previo...detailed

112-00-5Relevant articles and documents

Alkylation of ammonium salts catalyzed by imidazolium-based ionic liquid catalysts

Zheng, Zhuo Qun,Wang, Jie,Wu, Ting Hua,Zhou, Xiao Ping

, p. 1095 - 1101 (2008/03/27)

Quaternary ammonium salts were synthesized from ammonium salts and dialkyl carbonates over imidazolium ionic liquid catalysts. The reaction gave almost stoichiometric amounts of the quaternary ammonium salts for halides and nitrates. It was found that the electron-donating property of the alkyl moieties of ammonium cations, the electrophilic nature of the alkyl group of the carbonate, the acidity of the acid that the anion of the ammonium salt corresponds to, and the steric hindrance of the ammonium salts and the dialkyl carbonates are the key factors that influence the yields of quaternary ammonium salts. Strong electron-donating alkyl groups on the nitrogen atom of the ammonium salt, electron-withdrawing groups on the methylene carbon of dialkyl carbonate, and weaker steric hindrance of the starting ammonium salts and dialkyl carbonates favor the alkylation reaction of ammonium salts.

Fungicidal and bactericidal method

-

, (2008/06/13)

A fungicidal and bactericidal method of imparting fungicidal and bactericidal properties to an article by coating or impregnating the article with a solution of a quaternary ammonium salt of alginic acid or carboxymethyl cellulose (which is insoluble or sparingly soluble in water) in an organic solvent and thereafter removing the solvent from the article.

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