110271-24-4

Basic information

• Product Name: N-(3,4-dichlorobenzoyl)thiazolidine-4-carboxylic acid
• Synonyms: N-(3,4-dichlorobenzoyl)thiazolidine-4-carboxylic acid
• CAS NO: 110271-24-4
• Molecular Weight: 306.169
• Mol File: 110271-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3,4-dichlorobenzoyl)thiazolidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-dichlorobenzoyl)thiazolidine-4-carboxylic acid(110271-24-4)
• EPA Substance Registry System: N-(3,4-dichlorobenzoyl)thiazolidine-4-carboxylic acid(110271-24-4)

Safety Data

• Hazardous Substances Data: 110271-24-4(Hazardous Substances Data)

Upstream product

• 3024-72-4 3,4-dichlorobenzoyl chloride 
• 444-27-9 (RS)-4-thiazolidinecarboxylic acid 

Downstream Products

• 107124-32-3 2,2-dioxo-5-(3,4-dichlorophenyl)-6,7-bis(hydroxymethyl)-1,3-dihydropyrrolo<1,2-c>thiazole bis  
• 107124-27-6 dimethyl 2,2-dioxo-5-(3,4-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole-6,7-dicarboxylate 
• 107124-31-2 2,2-oxo-6,7-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole 
• 110271-32-4 2-oxo-6,7-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole bis 
• 110271-29-9 6,7-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole bis 
• 110271-27-7 6,7-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole 
• 110271-25-5 dimethyl 5-(3,3-dichlorophenyl)-1,3-dihydropyrrolo<1,2-c>thiazole-6,7-dicarboxylate 

Relevant articles and documents

Synthesis, Chemical Reactivity, and Antileukemic Activity of 5-Substituted 6,7-Bis(hydroxymethyl)pyrrolothiazole Biscarbamates and the Corresponding Sulfoxides and Sulfones

A series of bis(N-methylcarbamate) and bis derivatives of 5-substituted 6,7-bis(hydroxymethyl)pyrrolothiazoles was prepared.The compounds were tested for activity in vivo against P388 lymphocytic leukemia, and the chemical reactivities of the compounds were compared by using the model nucleophile 4-(4-nitrobenzyl)pyridine (NBP).The 5-(3,4-dichlorophenyl)-substituted biscarbamates 6b, 8b, and 12b were inactive and unreactive toward NBP.The 5-methyl-substituted bicarbamates 6a, 7a, 8a, 9a, 12a, and 13a were all active against murine P388 lymphocytic leukemia.The chemical reactivities of the active compounds depended on the oxidation state of the sulfur.The reactivity toward NBP followed the order S > SO >> SO2.The sulfones 12a and 13a are the most active compounds in this series, and their lack of reactivity toward NBP led to the suggestion that 12a and 13a are activated in vivo.