108977-87-3

Basic information

• Product Name: 6-methyl-3,5-diphenyl-1H-pyrazin-2-one
• Synonyms: 6-methyl-3,5-diphenyl-1H-pyrazin-2-one
• CAS NO: 108977-87-3
• Molecular Weight: 262.311
• Mol File: 108977-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-3,5-diphenyl-1H-pyrazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-3,5-diphenyl-1H-pyrazin-2-one(108977-87-3)
• EPA Substance Registry System: 6-methyl-3,5-diphenyl-1H-pyrazin-2-one(108977-87-3)

Safety Data

• Hazardous Substances Data: 108977-87-3(Hazardous Substances Data)

Upstream product

• 20721-18-0 6-methylpyrazin-2-one 
• 100-34-5 benzene diazonium chloride 
• 786652-79-7 [(1-methyl-2-oxo-2-phenyl-ethylcarbamoyl)-phenyl-methyl]-carbamic acid tert-butyl ester 
• 2900-27-8 2-(tert-butoxycarbonylamino)-2-phenylacetic acid 
• 48115-38-4 norepinephrine 

Relevant articles and documents

Concise synthesis of 1H-pyrazin-2-ones and 2-aminopyrazines

Convenient syntheses of 1H-pyrazin-2-ones and 2-aminopyrazines are described. By coupling Boc-protected amino acids with α-amino ketones or with amino alcohols and subsequent oxidation, 1H-pyrazin-2-ones were obtained. Transformation into the corresponding pyrazine triflates and substitution with primary or secondary amines led to 2-aminopyrazines. Since these syntheses take advantage of the use of readily available starting materials (e.g., amino acids, aminoalcohols and amines) a variety of the entitled structures can be obtained in few, high yielding steps.