108589-73-7

Basic information

• Product Name: 5S-amino-1R,2S,3S,4S-cyclohexanetetrol
• Synonyms: 5S-amino-1R,2S,3S,4S-cyclohexanetetrol
• CAS NO: 108589-73-7
• Molecular Weight: 163.174
• Mol File: 108589-73-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5S-amino-1R,2S,3S,4S-cyclohexanetetrol(CAS DataBase Reference)
• NIST Chemistry Reference: 5S-amino-1R,2S,3S,4S-cyclohexanetetrol(108589-73-7)
• EPA Substance Registry System: 5S-amino-1R,2S,3S,4S-cyclohexanetetrol(108589-73-7)

Safety Data

• Hazardous Substances Data: 108589-73-7(Hazardous Substances Data)

Upstream product

• 1157852-11-3 5S-azido-5-deoxy-1,2:3,4-di-O-isopropylidene-(+)-proto-quercitol 
• 1157852-10-2 1,2:3,4-di-O-isopropylidene-5R-O-mesyl-(+)-proto-quercitol 
• 1157852-09-9 1,2:3,4-di-O-isopropylidene-5R-(+)-proto-quercitol 
• 488-73-3 (+)-proto-quercitol 
• 1157852-12-4 5S-amino-5-deoxy-1,2:3,4-di-O-isopropylidene-(+)-proto-quercitol 
• 108391-64-6 3-acetamido-2,3-dideoxy-D-epi-inositol-1,4,5,6-tetraacetate 
• 108311-24-6 2,3-dideoxy-3-nitro-D-epi-inositol-1,4,5,6-tetraacetate 
• 28978-34-9 5,6-dideoxy-1,2-O-isopropyledine-6-nitro-α-D-xylo-hexofuranose 
• 108311-23-5 (1R,2S,3S,5S)-5-Nitro-cyclohexane-1,2,3,4-tetraol 
• 4969-33-9 3-O-acetyl-5,6-dideoxy-1,2-O-isopropylidene-6-C-nitro-α-D-xylo-hex-5-enofuranose 
• 56707-67-6 Acetic acid (3aR,5R,6S,6aR)-2,2-dimethyl-5-(2-nitro-ethyl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 108392-22-9 3-acetamido-2,3-dideoxy-D-epi-inositol 

Relevant articles and documents

N-arylmethylaminoquercitols, a new series of effective antidiabetic agents having α-glucosidase inhibition and antioxidant activity

Abstract A new series of N-arylalkylaminoquercitols were synthesized by reductive amination of aminoquercitol bisacetonide 5 and a variety of aryl aldehydes. The targeted N-substituted aminoquercitols having phenolic moiety (7a-7c) displayed significantly enhanced α-glucosidase inhibition, which is 26-32 times more potent than that of the unmodified aminoquercitol 6. In addition, compounds 7a-7c also retained antioxidant activity with relatively more pronounced potency than their original phenolics. This recent finding suggests an approach to develop effective antidiabetic agents by incorporating antioxidative moiety into aminocyclitol core structure.

Chemical synthesis of 3-amino-2,3-dideoxy-D-inositol (an intermediate in the biosynthesis of 2-deoxystreptamine) and its D-epi stereoisomers

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