1078719-18-2

Basic information

• Product Name: C₂₉H₃₆N₄O₇
• Synonyms: C₂₉H₃₆N₄O₇
• CAS NO: 1078719-18-2
• Molecular Weight: 552.627
• Mol File: 1078719-18-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₆N₄O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₆N₄O₇(1078719-18-2)
• EPA Substance Registry System: C₂₉H₃₆N₄O₇(1078719-18-2)

Safety Data

• Hazardous Substances Data: 1078719-18-2(Hazardous Substances Data)

Upstream product

• 41036-19-5 L-alanyl-alanine methylester hydrochloride 
• 269399-46-4 (Z)-5-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-pent-3-enoic acid 

Downstream Products

• 1078719-20-6 C₂₉H₃₆N₄O₈ 

Relevant articles and documents

Peptidyl epoxides extended in the P′ direction as cysteine protease inhibitors: Effect on affinity and mechanism of inhibition

Endo peptidyl epoxides, in which the central epoxidic moiety replaces the scissile amide bond of a P3-P3′ peptide, were designed as cysteine proteases inhibitors. The additional P′-S′ interactions, relative to those of an exo peptidyl epoxide of the same P3-P1 sequence, significantly improved affinity to the enzymes papain and cathepsin B, but also changed the mode of inhibition from active-site directed inactivation to reversible competitive inhibition. Computational models rationalize the binding affinity and the inhibition mechanism.