10601-73-7 Usage
Description
N-(3-Hydroxypropyl)acetamide is a versatile chemical compound belonging to the acetamides class. It is synthesized through the reaction of 3-chloro-1,2-propane-diol with acetamide. Characterized by the presence of a hydroxypropyl group attached to the acetamide functional group, this compound serves as a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure endows it with potential applications in drug delivery, controlled release systems, solvents, and reagents in chemical reactions across pharmaceutical and agricultural industries.
Uses
Used in Pharmaceutical Industry:
N-(3-Hydroxypropyl)acetamide is used as a building block for the synthesis of pharmaceuticals due to its ability to enhance the properties of drug molecules, such as solubility, stability, and bioavailability.
Used in Agrochemical Industry:
In the agrochemical industry, N-(3-Hydroxypropyl)acetamide is utilized as a precursor in the development of agrochemicals, contributing to the improvement of crop protection products and their effectiveness.
Used in Drug Delivery Systems:
N-(3-Hydroxypropyl)acetamide is employed as a component in drug delivery systems, particularly for controlled release applications. Its hydroxypropyl group allows for the attachment of drug molecules, enabling a sustained and targeted release of therapeutic agents.
Used as a Solvent:
N-(3-Hydroxypropyl)acetamide is used as a solvent in various chemical reactions within the pharmaceutical and agricultural industries, facilitating the dissolution of reactants and promoting reaction efficiency.
Used as a Reagent:
N-(3-Hydroxypropyl)acetamide serves as a reagent in chemical reactions, particularly in the synthesis of complex organic molecules and the modification of existing compounds to enhance their properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 10601-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,6,0 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10601-73:
(7*1)+(6*0)+(5*6)+(4*0)+(3*1)+(2*7)+(1*3)=57
57 % 10 = 7
So 10601-73-7 is a valid CAS Registry Number.
10601-73-7Relevant articles and documents
Synthesis of amide libraries with immobilized HOBt
Vokkaliga, Smitha,Jeong, Jeannie,Lacourse, William R.,Kalivretenos, Aristotle
, p. 2722 - 2724 (2011)
Highly reactive N-acylating solid-phase reagents based on macroporous polystyrene-bound 1-hydroxybenzotriazole (P-HOBt) and silica-bound 1-hydroxybenzotriazole (Si-HOBt) were prepared and compared for reactivity by synthesis of small combinatorial libraries of acetamides and benzamides.
Saegusa et al.
, p. 713,714 (1974)
METHOD FOR PREPARING SITE-SPECIFICALLY MODIFIED PROTEIN BASED ON NOVEL CARBON-CARBON BOND FORMATION
-
Paragraph 0099-0101, (2018/03/25)
A method for producing a site-specifically modified protein based on new carbon-carbon bond formation is disclosed, including the following three steps (marking, activation, and coupling steps): (a) marking of the modification site by incorporating a spec
Acetic acid as a catalyst for the N-acylation of amines using esters as the acyl source
Sanz Sharley, Daniel D.,Williams, Jonathan M. J.
supporting information, p. 2020 - 2023 (2017/02/15)
We report a cheap and simple method for the acetylation of a variety of amines using catalytic acetic acid and either ethyl acetate or butyl acetate as the acyl source. Catalyst loadings as low as 10 mol% afforded acetamide products in excellent yields at temperatures ranging from 80-120 °C. The methodology can also be successfully applied for the synthesis of a broad range of other amides, including the formation of formamides at 20 °C.
