105546-92-7Relevant articles and documents
A kind of marked estrogen sulfate conjugate and its preparation method
-
Paragraph 0101, (2017/03/28)
The invention discloses a 14C-labelled estrogen sulfate conjugate and a preparation method thereof, and belongs to the field of radioactive isotope 14C-labelled compounds. The preparation method of the 14C-labelled estrogen sulfate conjugate disclosed by the invention comprises introducing a 14C radioactive isotope label in the structure of the estrogen sulfate conjugate, wherein the 14C label lotus is at C-3. A test result of the radioautography-multifunctional scanning and imaging system indicates that radioactive purity reaches 98%, and the synthesized 14C-labled compound provides conditions for researching trend of the estrogen sulfate conjugate in the environment.
A fusion method for the preparation of steroid sulfates
Dusza,Joseph,Bernstein
, p. 317 - 323 (2007/10/02)
A method for the preparation of steroid triethylammonium sulfates is outlined which involves the fusion of triethylamine-sulfur trioxide and steroids. Experimental details are presented which define the process as a thermal equilibrium resulting in the preferential sulfation of aliphatic hydroxyl groups. Salfation of an aromatic hydroxyl group can be achieved in the absence of an aliphatic hydroxyl group. With excess reagent both types of hydroxyl groups in the same molecule can be sulfated.
