105300-90-1

Basic information

• Product Name: 4-(BOC-4-AMINOPHENYL)-BUTANOIC ACID
• Synonyms: 4-(BOC-4-AMINOPHENYL)-BUTANOIC ACID
• CAS NO: 105300-90-1
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.33
• Mol File: 105300-90-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(BOC-4-AMINOPHENYL)-BUTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(BOC-4-AMINOPHENYL)-BUTANOIC ACID(105300-90-1)
• EPA Substance Registry System: 4-(BOC-4-AMINOPHENYL)-BUTANOIC ACID(105300-90-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 105300-90-1(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 15118-60-2 4-(4-aminophenyl)butyric Acid 
• 625-38-7 but-3-enoic acid 
• 380430-49-9 [4-(tert-butoxycarbonylamino)phenyl]boronic acid 

Downstream Products

• 1146975-05-4 4-[4-(t-Butoxycarbonylamino)phenyl]butanamide 
• 1021853-55-3 cyclopentyl N-(4-{4-[(tert-butoxycarbonyl)amino]phenyl}butanoyl)-L-leucinate 

Relevant articles and documents

Development of a new traceless aniline linker for solid-phase synthesis of azomethines. Application to parallel synthesis of a rod-shaped liquid crystalline library

A new traceless linker was developed to synthesize a library of 42 compounds possessing an azomethine linkage using combinatorial solid-phase parallel synthesis. The loading of the substrates on a solid support and cleavage from the solid support were performed by an imine synthesis and by imine-exchanged process under mild conditions, respectively. Thioesters with a hydroxy group on the central core exhibited liquid crystalline properties with the widest transition temperatures in the library.

DIARYLHYDANTOIN COMPOUNDS

The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Antihypertensive dihydropyridine compositions, optical isomers and intermediates

Compositions containing dihydropyridine derivatives which are useful for treating congestive heart failure, hypertension, or angina have the formula: STR1 or a pharmaceutically acceptable acid addition salt thereof, wherein n is an integer from 0 to 8; Y is --O--, --NH--, --NR2 --, --S--, --S(O)--, --S(O)2 --, or a bond; R1 and R2 are each independently A1, A2, A3 or A4 where A1 is --(CH2)m (CHOH)p CH2 OH; A2 is --(CH2)q CH(3-r) [(CH2)s OH]r ; A3 is --(CH2)q CH(3-r) [(CH2)p COOR3 ]r ; and A4 is --(CH2)m COOR3 ; where m is an integer from 1 to 8; p is an integer from 0 to 4; q is an integer from 0 to 8; r is 2 or 3; s is an integer from 1 to 4; and R3 is H or alkyl of 1 to 18 carbon atoms; R4 is --NO2, --CF3, or halo; and R5 is lower alkyl or --CH2 CH2 OCH3. Also disclosed are optical isomers of the above compounds, as well as intermediates in the preparation of these final products.