1049693-98-2 Usage
Description
(4-[(4-methylphenyl)sulfonyl]oxyphenyl)boronic acid is a chemical compound that features a boronic acid group attached to a phenyl ring. This phenyl ring has a sulfonyloxy group linked to it, which is further connected to a methylphenyl group. (4-[(4-methylphenyl)sulfonyl]oxyphenyl)boronic acid is known for its ability to form stable complexes with Lewis bases, making it a useful reagent in organic synthesis and a promising candidate for various applications in different fields.
Uses
Used in Organic Synthesis:
(4-[(4-methylphenyl)sulfonyl]oxyphenyl)boronic acid is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds. Its application is particularly significant in the Suzuki-Miyaura cross-coupling reaction, a widely used method in organic chemistry for the formation of new carbon-carbon bonds.
Used in Catalysis and Metal-Catalyzed Reactions:
The boronic acid functionality of this compound allows it to form stable complexes with Lewis bases, making it a valuable asset in catalysis. It can also serve as a ligand in metal-catalyzed reactions, further expanding its utility in the field of chemistry.
Used in Medicinal Chemistry and Drug Discovery:
The presence of the sulfonyloxy group and the aromatic rings in (4-[(4-methylphenyl)sulfonyl]oxyphenyl)boronic acid gives it potential for use as a pharmacophore. This means it can be employed in the design and development of new drugs, contributing to advancements in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 1049693-98-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,6,9 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1049693-98:
(9*1)+(8*0)+(7*4)+(6*9)+(5*6)+(4*9)+(3*3)+(2*9)+(1*8)=192
192 % 10 = 2
So 1049693-98-2 is a valid CAS Registry Number.
1049693-98-2Relevant articles and documents
Preparation method of hydroxyphenylboronic acid
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Paragraph 0050; 0052, (2020/05/08)
The invention discloses a preparation method of hydroxyphenylboronic acid, which belongs to the technical field of boric acid synthesis in medical intermediates. The method comprises the following steps: starting from bromophenol, carrying out BOC, trimethylsilyl or benzyl protection, forming a Grignard reagent, reacting with borate, or carrying out one-pot reaction with borate and n-butyllithium,and hydrolyzing to obtain hydroxyphenylboronic acid. According to the invention, cheap and easily available protecting groups are adopted, so that the protecting groups are easy to remove during boronation reaction hydrolysis, industrial amplification is easy to realize, batch production is carried out on the scale of dozens of kilograms, and the process stability is good.
