104617-86-9 Usage
Description
(±)-PraMipexole, also known as Pramipexole, is a recemic analogue of (S)-Pramipexole (P700755), which is a dopamine-D2-receptor agonist. It is a pharmaceutical compound that has been synthesized to target and activate specific dopamine receptors in the brain, playing a crucial role in the treatment of certain neurological conditions.
Uses
Used in Pharmaceutical Industry:
(±)-PraMipexole is used as an antiparkinsonian agent for the treatment of Parkinson's disease. It helps alleviate the symptoms of the disease by mimicking the effects of dopamine, a neurotransmitter that is often deficient in Parkinson's patients. This leads to improved motor function and a reduction in the severity of symptoms such as tremors, rigidity, and bradykinesia.
Additionally, (±)-PraMipexole has been found to have potential applications in other areas of medicine, such as the treatment of restless legs syndrome and certain types of depression. However, these uses are still under investigation and may require further research to confirm their efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 104617-86-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,6,1 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 104617-86:
(8*1)+(7*0)+(6*4)+(5*6)+(4*1)+(3*7)+(2*8)+(1*6)=109
109 % 10 = 9
So 104617-86-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)
104617-86-9Relevant articles and documents
A preparation method of pramipexole hydrochloride (by machine translation)
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, (2019/02/04)
The invention discloses a method for preparation of pramipexole hydrochloride, comprises the following steps: to amino cyclohexyl [...] acyl chloride condensation for protecting amino group to obtain the propionyl cyclohexanol, then is obtained by catalyt
NOVEL PROCESS FOR SYNTHESIS OF PRAMIPEXOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
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Page/Page column 13-14, (2008/12/08)
The present invention relates to a novel process for synthesis of pramipexole, shown in the synthesis scheme. Formulae (I), (II), (III), (IV), (V) and (VI).
METHOD FOR THE RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL AND INTERMEDIATE COMPOUNDS
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Page/Page column 8, (2008/06/13)
The invention relates to a novel method for the resolution of the racemic mixture of compound (R,S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole, or the enrichment of same with in one of its enantiomers, and to intermediate compounds which can be used to perform said method.