104147-32-2

Basic information

• Product Name: 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline
• Synonyms: 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline;3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)benzenamine
• CAS NO: 104147-32-2
• Molecular Formula: C₈H₅Cl₂F₄NO
• Molecular Weight: 278.03
• EINECS: 401-790-3
• Product Categories: Intermediate
• Mol File: 104147-32-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 305 °C
• Flash Point: 138 °C
• Appearance: Kind of white to yellow powder
• Density: 1.558
• Vapor Pressure: 0.000834mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: 2-8°C
• PKA: 1.82±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline(104147-32-2)
• EPA Substance Registry System: 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline(104147-32-2)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-50/53
• Safety Statements: 24/25-26-57-60-61
• Hazardous Substances Data: 104147-32-2(Hazardous Substances Data)

Usage

Description

3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline is a halogenated organic compound with the molecular formula C8H6Cl2F4NO. It is a synthetic compound that incorporates both chlorine and fluorine atoms, which contribute to its unique chemical properties and applications.
Used in Pharmaceutical Industry:
3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of different drugs, enhancing their therapeutic effects and properties.
Used in Agrochemical Industry:
3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline is used as a precursor in the development of agrochemicals, particularly as a pesticide and herbicide, due to its capacity to inhibit the growth of certain plants and pests, thereby protecting crops from damage.
Used in Industrial Chemicals:
3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline is utilized in the production of other industrial chemicals, where its unique combination of chlorine and fluorine atoms provides specific chemical reactivity and stability required for various applications.

InChI:InChI=1/C8H5Cl2F4NO/c9-4-1-3(15)2-5(10)6(4)16-8(13,14)7(11)12/h1-2,7H,15H2

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 5930-28-9 4-amino-2,6-dichlorophenol 
• 87-65-0 2,6-Dichlorophenol 

Downstream Products

• 104147-33-3 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenylisocyanate 
• 1415750-46-7 2-((6-chloropyridin-3-yl)methoxy)-N-(3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl)benzamide 
• 1261132-07-3 N-[2-(cyclohexylamino)-1-(3-fluorophenyl)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261132-04-0 N-[2-(cyclohexylamino)-2-oxo-1-m-tolylethyl]-N-(3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261132-13-1 N-[2-(cyclohexylamino)-1-(2-methoxyphenyl)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261132-14-2 N-[2-(cyclohexylamino)-1-(3-methoxyphenyl)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261132-06-2 N-[2-(cyclohexylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261132-12-0 N-[2-(cyclohexylamino)-1-(3-hydroxyphenyl)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 
• 1261131-99-0 N-[1-(3-chlorophenyl)-2-(cyclohexylamino)-2-oxoethyl]-N-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 

Relevant articles and documents

Production technology of 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)benzenamine

The invention discloses a production technology of 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)benzenamine, and relates to the technical field of chemical product production. 2,6-dichlorophenol and nitric acid are mixed to be subjected to a nitration reaction, and 2,6-dichloro-4-nitrophenol (DCNP) is obtained; the 2,6-dichloro-4-nitrophenol (DCNP) is subjected to a reduction reaction in hydrogen, and 4-amino-2,6-dichlorophenol (DCAP) is obtained; then, the 4-amino-2,6-dichlorophenol (DCAP) and tetrafluoroethylene are subjected to an addition reaction, and 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)benzenamine is obtained. The reaction purpose is strong, few by-products are produced, the conversion rate is high, and postprocessing is easy.