103532-27-0

Basic information

• Product Name: diltiazem hydrochloride
• Synonyms: 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (2R-trans)-;(2R-trans)-DiltiazeM Hydrochloride;(+)-trans-DiltiazeM Hydrochloride;(2R-trans)-3-(Acetyloxy)-5-[2-(diMethylaMino)ethyl]-2,3-dihydro-2-(4-Methoxyphenyl) -1,5-benzothiazepin-4(5H)-one Monohydrochloride
• CAS NO: 103532-27-0
• Molecular Formula: C22H27ClN2O4S
• Molecular Weight: 0
• Product Categories: Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 103532-27-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: diltiazem hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: diltiazem hydrochloride(103532-27-0)
• EPA Substance Registry System: diltiazem hydrochloride(103532-27-0)

Safety Data

• Hazardous Substances Data: 103532-27-0(Hazardous Substances Data)

Usage

Description

Diltiazem hydrochloride is a medication belonging to the calcium channel blocker class, chemically known as (2S,3S)-3-(acetyloxy)-5-[(2-aminoethyl)methylamino]-2-(4-methoxyphenyl)-2-oxazolidineacetic acid, monohydrochloride. It is used to treat various cardiovascular conditions, such as hypertension, angina, and arrhythmias, by relaxing blood vessel walls and increasing blood flow.

Uses

Used in Pharmaceutical Industry:
Diltiazem hydrochloride is used as an antihypertensive agent for treating high blood pressure. It helps to lower blood pressure by dilating blood vessels, allowing for better blood flow and reducing the workload on the heart.
Used in Cardiology:
Diltiazem hydrochloride is used as an antianginal agent for managing chest pain (angina) caused by insufficient blood supply to the heart. It helps to relax the coronary arteries, increasing blood flow to the heart muscle and reducing the severity of angina.
Used in Arrhythmia Treatment:
Diltiazem hydrochloride is used as an antiarrhythmic agent for treating irregular heartbeats (arrhythmias). It slows down the electrical impulses in the heart, helping to regulate the heart's rhythm and maintain a normal heartbeat.
Used in Drug Delivery Systems:
Diltiazem hydrochloride can be incorporated into various drug delivery systems, such as extended-release formulations or transdermal patches, to improve patient compliance and provide a controlled release of the medication over time. This can help to maintain a consistent therapeutic level of the drug in the body and reduce the frequency of dosing.