10352-63-3 Usage
Description
Chloromethanesulfonic acid, also known as sodium chloromethanesulfonate, is an organic compound with the chemical formula CH3ClSO3Na. It is a colorless to pale yellow crystalline solid that is soluble in water. Chloromethanesulfonic acid is a strong electrophile and a highly reactive chemical, which makes it useful in various chemical reactions and applications.
Uses
1. Used in Ion Exchange Resins:
Chloromethanesulfonic acid is used as a key component in the preparation of carboxymethyl (CM) pullulan and sulfomethyl (SM) pullulan ion exchange resins. These resins are essential in various industrial processes, including water treatment, purification of chemicals, and separation of biological molecules.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, chloromethanesulfonic acid is utilized as an intermediate for the synthesis of various drugs and drug candidates. Its reactivity allows for the formation of new chemical bonds and the creation of diverse molecular structures with potential therapeutic applications.
3. Used in Chemical Synthesis:
Chloromethanesulfonic acid is employed as a reagent in the synthesis of a wide range of organic compounds, such as dyes, pesticides, and other specialty chemicals. Its strong electrophilic nature enables it to participate in various chemical reactions, making it a valuable tool in the synthesis of complex molecules.
4. Used in Research and Development:
Due to its unique chemical properties, chloromethanesulfonic acid is often used in research and development for the exploration of new chemical reactions and the development of novel compounds with potential applications in various industries, including pharmaceuticals, materials science, and environmental science.
Check Digit Verification of cas no
The CAS Registry Mumber 10352-63-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,5 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10352-63:
(7*1)+(6*0)+(5*3)+(4*5)+(3*2)+(2*6)+(1*3)=63
63 % 10 = 3
So 10352-63-3 is a valid CAS Registry Number.
InChI:InChI=1/CH3ClO3S/c2-1-6(3,4)5/h1H2,(H,3,4,5)
10352-63-3Relevant articles and documents
Protocol for Stereoselective Construction of Highly Functionalized Dienyl Sulfonyl Fluoride Warheads
Zhang, Zai-Wei,Wang, Shi-Meng,Fang, Wan-Yin,Lekkala, Ravindar,Qin, Hua-Li
, p. 13721 - 13734 (2020/12/15)
A pyrrolidine-mediated Knoevenagel-type reaction for highly stereoselective construction of novel α-halo-1,3-dienylsulfonyl fluorides was achieved in up to 100% Z-selectivity and high yields at room temperature from condensation of the readily available aldehydes and halomethanesulfonyl fluorides. This protocol provided a class of unique α-halo-1,3-dienylsulfonyl fluorides with wide scope and excellent functional group compatibility. The α-halo-1,3-dienylsulfonyl fluorides were used as versatile building blocks in sulfur fluoride exchange click chemistry, Suzuki reaction, and Sonogashira reaction for the assembly of highly functionalized dienyl sulfonyl fluoride derivatives to be applied as covalent warheads for the discovery of new drugs.
