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  • (S)-3-(4-(2-amino-6-chloropyrimidin-4-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid

    Cas No: 1033804-86-2

  • USD $ 1.2-5.0 / Kiloliter

  • 5 Kiloliter

  • 3000 Metric Ton/Month

  • Chemwill Asia Co., Ltd.
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  • L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-/ LIDE PHARMA- Factory supply / Best price

    Cas No: 1033804-86-2

  • USD $ 10.0-10.0 / Gram

  • 1 Gram

  • 10 Metric Ton/Day

  • LIDE PHARMACEUTICALS LIMITED
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  • 1033804-86-2 Structure
  • Basic information

    1. Product Name: L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-
    2. Synonyms: L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-;(S)-3-(4-(2-amino-6-chloropyrimidin-4-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid;(2S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid;LX1606 intermediate;(S)-3-[4-(2-Amino-6-chloropyrimidin-4-yl)phenyl]-2-[(tert-butoxycarbonyl)amino]propionic acid;4-(2-Amino-6-chloro-4-pyrimidinyl)-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine;(2S)-3-[4-(2-Amino-6-chloropyrimidin-4-yl)phenyl]-2-[(tert-butoxycarbonyl)amino]propionic acid;(S)-3-(4-(2-amino-6-chloropyrimidin-4-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
    3. CAS NO:1033804-86-2
    4. Molecular Formula: C18H21ClN4O4
    5. Molecular Weight: 392.83674
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1033804-86-2.mol
    9. Article Data: 6
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-(1033804-86-2)
    11. EPA Substance Registry System: L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]-(1033804-86-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1033804-86-2(Hazardous Substances Data)

1033804-86-2 Usage

Description

L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]is a complex chemical compound that combines the essential amino acid L-phenylalanine with a pyrimidine derivative. L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]is significant for its role in the synthesis of proteins and neurotransmitters, as well as its utility in pharmaceuticals as a precursor for the development of various medications. Its potential therapeutic applications and use as a building block for new drugs make it a valuable compound in the medical and pharmaceutical fields.

Uses

Used in Pharmaceutical Industry:
L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]is used as a precursor in the synthesis of various medications for its ability to contribute to the development of new pharmaceutical compounds.
Used in Medical Research:
L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]is utilized as a research tool in the exploration of potential therapeutic applications, particularly in the treatment of certain diseases, due to its unique structure and properties.
Used in Drug Development:
L-Phenylalanine, 4-(2-aMino-6-chloro-4-pyriMidinyl)-N-[(1,1-diMethylethoxy)carbonyl]is employed as a building block in drug development, where its integration into new molecular structures could lead to the creation of innovative treatments for a range of medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1033804-86-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,3,8,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1033804-86:
(9*1)+(8*0)+(7*3)+(6*3)+(5*8)+(4*0)+(3*4)+(2*8)+(1*6)=122
122 % 10 = 2
So 1033804-86-2 is a valid CAS Registry Number.

1033804-86-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-3-(4-(2-amino-6-chloropyrimidin-4-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid

1.2 Other means of identification

Product number -
Other names (2S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1033804-86-2 SDS

1033804-86-2Downstream Products

1033804-86-2Relevant articles and documents

Process Development of Tryptophan Hydroxylase Inhibitor LX1031, a Drug Candidate for the Treatment of Irritable Bowel Syndrome

Bednarz, Mark S.,Iimura, Shinya,Kanamarlapudi, Ramanaiah C.,Lim, Ngiap-Kie,Wu, Wenxue,Yan, Jie,Zhang, Haiming,Zhao, Matthew M.

, p. 261 - 273 (2020/03/10)

Two process routes for LX1031, a tryptophan hydroxylase inhibitor for the treatment of irritable bowel syndrome, were developed. They shared the same left-hand and right-hand starting materials as well as the penultimate intermediate. The chiral center in

SOLID FORMS OF (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-2,2,2-TRIFLUORO-1-(3'-METHOXYBIPHENYL- 4-YL)ETHOXY)PYRIMIDIN-4-YL)PHENYL) PROPANOIC ACID AND METHODS OF THEIR USE

-

Page/Page column 8, (2009/04/24)

Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-2,2,2-trifluoro-1-(3'-methoxybiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid and salts thereof are disclosed

METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS

-

Page/Page column 9, (2009/04/24)

Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.

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