102604-08-0Relevant articles and documents
Nucleotides; Part XXXVI A New Synthesis of 9-(β-D-Ribofuranosyl)uric Acid and its 5'-Monophosphate
Schulz, Bernd S.,Pfleiderer, Wolfgang
, p. 210 - 218 (2007/10/02)
Syntheses for 9-(β-D-ribofuranosyl)uric acid (16) and its 5'-monophosphate 14 have been achieved starting from guanosine and applying the 2-(?-nitrophenyl)ethyl group for protection of the aglycon moiety as well as the phosphate function.A more effficient and direct approach to 14 uses O6,O8-dibenzyl protection and phosphorylation by the Yoshikawa procedure.The various protected intermediates have been characterized by spectroscopic means and elemental analysis.