101054-93-7

Basic information

• Product Name: 4,4,4-TRIFLUORO-2-BUTANOL
• Synonyms: 4,4,4-TRIFLUORO-2-BUTANOL;4,4,4-TRIFLUORO-BUTAN-2-OL;4,4,4-TRIFLUORO-2-BUTANOL, 97% MIN.;2-Hydroxy-4,4,4-trifluorobutane;3-Hydroxy-1,1,1-trifluorobutane
• CAS NO: 101054-93-7
• Molecular Formula: C₄H₇F₃O
• Molecular Weight: 128.09
• Mol File: 101054-93-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 104.047 °C at 760 mmHg
• Flash Point: 54.35 °C
• Appearance: /
• Density: 1.177 g/cm³
• Vapor Pressure: 17.289mmHg at 25°C
• Refractive Index: 1.335
• PKA: 14.16±0.20(Predicted)
• CAS DataBase Reference: 4,4,4-TRIFLUORO-2-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-TRIFLUORO-2-BUTANOL(101054-93-7)
• EPA Substance Registry System: 4,4,4-TRIFLUORO-2-BUTANOL(101054-93-7)

Safety Data

• Hazardous Substances Data: 101054-93-7(Hazardous Substances Data)

Usage

General Description

4,4,4-Trifluoro-2-butanol is a chemical compound with the molecular formula C4H7F3O. It is a colorless liquid with a strong odor and is commonly used as a solvent, intermediate in organic synthesis, and as a reagent in pharmaceutical and agricultural applications. 4,4,4-TRIFLUORO-2-BUTANOL is highly reactive and can easily undergo chemical reactions such as oxidation and esterification. It is also known for its potential to cause irritation to the eyes, skin, and respiratory system, and should be handled with caution. Additionally, 4,4,4-Trifluoro-2-butanol is considered a potentially hazardous substance and should be used and stored according to proper safety guidelines and regulations.

InChI:InChI=1/C4H7F3O/c1-3(8)2-4(5,6)7/h3,8H,2H2,1H3

Upstream product

• 2314-97-8 iodotrifluoromethane 
• 5689-83-8 4-methyl-[1,3,2]dioxathiolane 2,2-dioxide 
• 758-33-8 1,1,1-Trifluor-2-butanamin-hydrochlorid 
• 84153-82-2 4,4,4-trifluorobutan-1-amine hydrochloride 
• 101055-00-9 4,4,4-trifluorobutan-2-amine hydrochloride 
• 2366-70-3 4,4,4-trifluorobutan-2-one 

Downstream Products

• 1351094-59-1 N-methyl-3-nitro-4-[(3,3,3-trifluoro-1-methylpropyl)oxy]benzenesuIfonamide 

Relevant articles and documents

Nucleophilic trifluoromethylation of imines using the CF3I/TDAE reagent

The nucleophilic trifluoromethylation reagent derived from CF3I and tetrakis(dimethylamino)-ethylene (TDAE) was found to be effective in addition to both N-tosyl aldimines and N-tolyl sulfinimines, the latter reaction exhibiting very good diastereoselectivity.

Process for trifluoromethylation of sulfates

The subject invention relates to a process for the trifluoromethylation of sulfates, including cyclic and acyclic sulfates. The subject invention further pertains to the compounds produced by the trifluoromethylation of sulfates.

When is a trifluoromethyl group more lipophilic than a methyl group? Partition coefficients and selected chemical shifts of aliphatic alcohols and trifluoroalcohols

-