10093-54-6 Usage
Description
17β-estradiol enanthate, also known as 17α-Estra-1,3,5(10)-triene-3,17-diol-17-heptanoate, is a synthetic estrogen hormone derived from estradiol. It is characterized by the presence of a heptanoate ester attached to the 17β-hydroxyl group, which enhances its lipophilicity and allows for a longer duration of action compared to other forms of estradiol. This modification makes it suitable for various medical applications, particularly in hormone replacement therapy and the treatment of certain conditions related to estrogen deficiency.
Uses
Used in Hormone Replacement Therapy:
17β-estradiol enanthate is used as a hormone replacement agent for the treatment of menopausal symptoms, such as hot flashes, night sweats, and vaginal atrophy. It helps to alleviate these symptoms by providing the body with the necessary estrogen levels, thereby restoring hormonal balance and improving overall well-being.
Used in Treating Estrogen Deficiency Conditions:
17β-estradiol enanthate is used as a therapeutic agent for treating conditions related to estrogen deficiency, such as osteoporosis and hypogonadism. By supplementing the body with the required estrogen levels, it helps to prevent bone loss, maintain bone density, and support the development and function of sexual organs.
Used in Neuroprotection and Neurodegenerative Disease Management:
17β-estradiol enanthate is used as a neuroprotective agent for the treatment and management of neurodegenerative diseases, such as Alzheimer's disease. It has been shown to possess neuroprotective properties, which can help to slow down the progression of cognitive decline and improve the overall quality of life for patients suffering from these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 10093-54-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,9 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10093-54:
(7*1)+(6*0)+(5*0)+(4*9)+(3*3)+(2*5)+(1*4)=66
66 % 10 = 6
So 10093-54-6 is a valid CAS Registry Number.
10093-54-6Relevant articles and documents
Stability-indicating analysis of injectable estrogen-androgen combinations in formulations containing corn oil
Roman,Yates,Millar,O'Neill,Zweig
, p. 733 - 736 (1979)
A method was developed for the analysis of testosterone 17-enanthate 3-benzilic acid hydrazone, 17-β-estradiol 3,17-dienanthate, an estradiol benzoate combinations dissolved in an oily vehicle. Testosterone 17-enanthate 3-benzilic acid hydrazone was separated from the other drugs and vehicle components by chromatography on an acetonitrile-infusorial earth column followed by quantitation using UV spectroscopy. The estradiol esters were separated from the oil by an additional chromatographic step using a heptane-silanized infusorial earth column prior to quantitation by GLC. Subjecting formulations to elevated temperatures resulted in detectable losses for testosterone 17-enanthate 3-benzilic acid hydrazone and 17-β-estradiol 3,17-dienanthate. For both drugs, degradation was due to hydrolysis; the degradation products, testosterone 17-enanthate and 17-β-estradiol 17-enanthate, did not interfere with the intact drug determination. Methods also were developed to estimate degradation product levels in the formulation.
