100621-86-1

Basic information

• Product Name: Methanol, (phenylthio)-, benzoate
• CAS NO: 100621-86-1
• Molecular Formula: C14H12O2S
• Molecular Weight: 244.314
• Mol File: 100621-86-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanol, (phenylthio)-, benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methanol, (phenylthio)-, benzoate(100621-86-1)
• EPA Substance Registry System: Methanol, (phenylthio)-, benzoate(100621-86-1)

Safety Data

• Hazardous Substances Data: 100621-86-1(Hazardous Substances Data)

Upstream product

• 26905-22-6 hydroxymethyl phenyl sulfide 
• 98-88-4 benzoyl chloride 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 93-97-0 benzoic acid anhydride 
• 64-17-5 ethanol 
• 67-66-3 chloroform 
• 100-68-5 methyl-phenyl-thioether 
• 94-36-0 dibenzoyl peroxide 
• 614-45-9 tert-Butyl peroxybenzoate 
• 24420-59-5 methyl phenyl sulfonium bismethoxycarbonylmethylide 
• 7205-91-6 phenylthiomethyl chloride 
• 65-85-0 benzoic acid 
• 54086-42-9 (phenylsulfinylmethyl)-tri-n-butyltin 
• 6597-18-8 (dibenzoyloxyiodo)benzene 

Downstream Products

• 166331-78-8 fluoromethyl benzoate 
• 55887-44-0 benzyloxymethyl benzoate 
• 40796-19-8 benzyloxymethyl bromide 
• 35572-08-8 bromomethyl phenyl thioether 
• 5335-05-7 chloromethyl benzoate 
• 100622-06-8 benzenesulfonyl-benzoyloxy-methane 
• 26905-22-6 hydroxymethyl phenyl sulfide 

Relevant articles and documents

Gold-Catalyzed, Iodine(III)-Mediated Direct Acyloxylation of the Unactivated C(sp3)–H Bonds of Methyl Sulfides

The gold-catalyzed, iodine(III)-mediated direct oxidative acyloxylation of the C(sp3)–H bonds of methyl sulfides for the synthesis of various α-thioaryl and α-thioalkyl ester derivatives was discovered. Bis(acyloxy)iodobenzene proved to be an efficient reagent to activate the sulfur atom as an in situ directing group for α-C(sp3)–H functionalization. The attractive features of this protocol include short reaction times, low catalyst loading, and in situ activation of adjacent C(sp3)–H bonds of the sulfur atom.

Fe2O3-catalyzed Pummerer rearrangement of acyl chlorides and sulfoxides: Facile synthesis of alkylthiomethyl ester

A simple, effective approach for the Pummerer rearrangement of acyl chlorides with sulfoxides by using a low-cost and more abundant Fe catalyst has been described. The alkylthiomethyl ester products were prepared in good to excellent yields for a range of different substrates including asymmetrical sulfoxides and acyl chlorides with a variety of functional groups under mild reaction conditions. The reaction features short reaction time, simple manipulation, cheap reagents and a broad substrate scope. Single crystal X-ray analysis of a representative methylthiomethyl (MTM) group containing product was also reported.

Tin-Pummerer rearrangement in the synthesis of O,S-acetal derivatives

α-Thioalkyl esters and carbonates have been prepared by a tin-Pummerer rearrangement in reactions of α-stannylated sulfoxides with acid chlorides or chloroformates, respectively. Acid chlorides have a higher reactivity than chloroformates in this reaction. Acta Chemica Scandinavica 1997.