100613-09-0

Basic information

• Product Name: 2-phenylacetoxy-propionic acid ethyl ester
• Synonyms: 2-phenylacetoxy-propionic acid ethyl ester
• CAS NO: 100613-09-0
• Molecular Weight: 236.268
• Mol File: 100613-09-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenylacetoxy-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylacetoxy-propionic acid ethyl ester(100613-09-0)
• EPA Substance Registry System: 2-phenylacetoxy-propionic acid ethyl ester(100613-09-0)

Safety Data

• Hazardous Substances Data: 100613-09-0(Hazardous Substances Data)

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 103-80-0 phenylacetyl chloride 
• 7699-00-5 (R)-Ethyl lactate 
• 64-17-5 ethanol 
• 57057-80-4 ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate 
• 103-82-2 phenylacetic acid 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 1589533-22-1 3-phenyl-5-(hydroxymethyl)-4-methoxyfuran-2(5H)-one 
• 1589532-51-3 3-phenyl-7a-methyl-7,7a-dihydrofuran[3,2-d][1,2]oxathin-5,5-dioxide-2(4H)-one 
• 21053-95-2 γ-methyl-α-phenyltetronic acid 
• 1589533-12-9 C₁₂H₁₂O₃ 
• 1589533-33-4 C₁₄H₁₆O₆S 

Relevant articles and documents

Synthesis and anti-BVDV activity of novel δ-sultones in vitro: Implications for HCV therapies

In this study we report the synthesis and activity against bovine viral diarrhea virus (BVDV) of a novel series of bicycle δ-sultones containing γ-lactones. BVDV is responsible for major losses in cattle. Some of the synthesized δ-sultones showed pronounced anti-BVDV activity with EC 50 values of 0.12-1.0 μM and no significant cytotoxicity. Among them, the ortho bromosubstituted derivative 4f (EC50 = 0.12 μM) showed better antiviral activity than other derivatives and was 10 fold more that of than positive control ribavirin (EC50 = 1.3 μM). BVDV is also considered to be a valuable surrogate for the hepatitis C virus (HCV) in antiviral drug studies. The above results provided a novel candidate for the development of anti-HCV agents.