1005-73-8Relevant articles and documents
Burton,Johnson
, p. 5361 (1964)
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Feast,W.J. et al.
, p. 433 - 436 (1966)
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METHOD FOR PRODUCING 1H,2H-PERFLUOROCYCLOALKENE
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Paragraph 0078; 0079, (2019/08/20)
PROBLEM TO BE SOLVED: To provide a novel method for producing 1H,2H-perfluorocycloalkene. SOLUTION: In the present invention, 1H,1H,2H-perfluorocycloalkane represented by the following formula (I) is brought into contact with alkylamine in the presence of a water-insoluble solvent and water, to obtain 1H,2H-perfluorocycloalkene represented by the following formula (II). SELECTED DRAWING: None COPYRIGHT: (C)2019,JPO&INPIT
Synthesis of hydrofluorocycloolefins through dehydrofluorination of hydrofluorocycloalkanes in amide solvents
Zhang, Wenni,Zhang, Chengping,Guo, Qin,Lu, Fengniu,Quan, Hengdao
, (2019/07/17)
Hydrofluorocycloolefins have outstanding economic and environmental advantages, as well as huge application potentials owing to their zero ozone depletion potentials (ODP) values and low global warming potentials (GWP) values. The synthesis of hydrofluorocycloolefins through dehydrofluorination of hydrohalocycloalkanes in N,N-dimethylformamide (DMF) or N,N-dimethylacetamide (DMAC) was investigated. It was found that the presence of [sbnd]CHF[sbnd] is critical for efficient elimination of HF. The reaction using reagents containing [sbnd]CHF[sbnd] group proceeded very well, whereas elimination was much more difficult to occur for reactants without [sbnd]CHF[sbnd] group. Based on these results, a rational reaction mechanism was proposed.
Transition-Metal-Free Catalytic Hydrodefluorination of Polyfluoroarenes by Concerted Nucleophilic Aromatic Substitution with a Hydrosilicate
Kikushima, Kotaro,Grellier, Mary,Ohashi, Masato,Ogoshi, Sensuke
supporting information, p. 16191 - 16196 (2017/11/27)
A transition-metal-free catalytic hydrodefluorination (HDF) reaction of polyfluoroarenes is described. The reaction involves direct hydride transfer from a hydrosilicate as the key intermediate, which is generated from a hydrosilane and a fluoride salt. The eliminated fluoride regenerates the hydrosilicate to complete the catalytic cycle. Dispersion-corrected DFT calculations indicated that the HDF reaction proceeds through a concerted nucleophilic aromatic substitution (CSNAr) process.