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9016-01-7

Basic Information
CAS No.: 9016-01-7
Name: ORGOTEIN
Molecular Structure:
Molecular Structure of 9016-01-7 (ORGOTEIN)
Formula: Cu4Zn4++++++++++++++++
Molecular Weight: 515.744
Synonyms: Bovine copper-zinc superoxide dismutase;Einecs 232-771-6;Orgoteina;Orgoteina [inn-spanish];Orgoteine;Orgoteine [inn-french]
EINECS: 232-771-6
PSA: 0.00000
LogP: -0.02000
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Chemistry

Product Name: Orgoteins   
Synonyms of Orgotein (CAS NO.9016-01-7) : Bovine copper-zinc superoxide dismutase ; Ontosein  ; Orgoteinum ; Palosein CAS NO:9016-01-7 

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD subcutaneous > 100mg/kg (100mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
monkey LD intramuscular > 60mg/kg (60mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
monkey LD intravenous > 100mg/kg (100mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
mouse LD oral > 5500mg/kg (5500mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
mouse LD subcutaneous > 5500mg/kg (5500mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
mouse LD50 intravenous 4435mg/kg (4435mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
mouse LDLo intraperitoneal 60mg/kg (60mg/kg) GASTROINTESTINAL: PERITONITIS

KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"
Toxicology and Applied Pharmacology. Vol. 26, Pg. 184, 1973.
rabbit LD subcutaneous > 40mg/kg (40mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
rabbit LDLo intravenous 10mg/kg (10mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Toxicology and Applied Pharmacology. Vol. 26, Pg. 184, 1973.
rat LD intraperitoneal > 5500mg/kg (5500mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
rat LD oral > 5500mg/kg (5500mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
rat LD subcutaneous > 5500mg/kg (5500mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.
rat LD50 intravenous 4435mg/kg (4435mg/kg)   European Journal of Rheumatology and Inflammation. Vol. 4, Pg. 173, 1981.

 

Safety Profile

 Orgotein (CAS NO.9016-01-7) is poisonous by intravenous and intraperitoneal routes. Orgotein (CAS NO.9016-01-7) is an experimental teratogen.