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| CAS No.: | 24853-80-3 |
|---|---|
| Name: | Azaphen hydrochloride |
| Molecular Structure: | |
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| Formula: | C16H19N5O.2HCl |
| Molecular Weight: | 370.28 |
| Synonyms: | 5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, dihydrochloride (8CI,9CI);2-(4-Methylpiperazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;2-(4-Methylpipirazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;Azafen;Azaphen; |
| Boiling Point: | 536 °C at 760 mmHg |
| Flash Point: | 278 °C |
| PSA: | 44.73000 |
| LogP: | 3.77390 |
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Chemistry
Chemical Name: Azaphen hydrochloride
IUPAC NAME: 5-Methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine dihydrochloride
CAS No.: 24853-80-3
Molecular Formula: C11H8N2O
Molecular Weight: 184.19 g/mol
Flash Point: 278 °C
Boiling Point: 536 °C at 760 mmHg
Following is the structure of Azephen (CAS No.24853-80-3):
The chemical synonymous of Azephen (CAS No.24853-80-3) are Azaphenonxazine ; Azaphen ; 2-(4-Methyl-1-Piperazinyl)-10-Methyl-3,4-Diazphenoxazine Dihydrochloride ; Azaphen Hydrochloride ; Azaphenonxazine 2HCL ; 2-(4-Methyl-1-Piperazinyl)-10-Methyl-3,4-Diazaphenoxazine Dihydrochloride
Toxicity Data With Reference
| 1. | orl-rat LD50:1 g/kg | ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. | ||
| 2. | scu-rat LD50:490 mg/kg | ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. | ||
| 3. | ivn-rat LD50:48 mg/kg | ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. | ||
| 4. | orl-mus LD50:700 mg/kg | PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 4 (1970),118. | ||
| 5. | scu-mus LD50:330 mg/kg | ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. | ||
| 6. | ivn-mus LD50:63 mg/kg | RPTOAN Russian Pharmacology and Toxicology. Translation of FATOAO. 37 (1974),2. | ||
| 7. | orl-cat LD50:200 mg/kg | ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. An antidepressant.