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CAS No.: | 2188-68-3 |
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Name: | Lycorine hydrochloride |
Molecular Structure: | |
Formula: | C16H17NO4.HCl |
Molecular Weight: | 323.776 |
Synonyms: | 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)- (9CI);Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1a,2b)-;Lycoran-1a,2b-diol, 3,3a-didehydro-, hydrochloride (8CI);Licorin hydrochloride; |
Melting Point: | 210-212oC |
Boiling Point: | 477.4 °C at 760 mmHg |
Flash Point: | 242.5 °C |
Appearance: | fine crystal powder. |
Hazard Symbols: | |
Risk Codes: | 25 |
Safety: | 45 |
Transport Information: | UN 2811 6.1/PG 3 |
PSA: | 62.16000 |
LogP: | 0.68650 |
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Molecular Structure:
Molecular Formula: C16H18ClNO4
Molecular Weight: 323.7714
Systematic Name: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride (1:1)
Synonyms of Lycorine hydrochloride (CAS NO.2188-68-3): Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- ; Licorin hydrochloride ; Lycorine HCl ; Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride
CAS NO: 2188-68-3
Classification Code: Peptidyl transferaseCell Signaling and Neuroscience ; Enzyme Inhibitors by Enzyme ; Gene Regulation and Expression ; P to ; RNA-Protein Translation Inhibitors
Flash Point: 242.5 °C
Enthalpy of Vaporization: 78.09 kJ/mol
Boiling Point: 477.4 °C at 760 mmHg
Vapour Pressure: 6.37E-10 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 117mg/kg (117mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. | |
mouse | LD50 | intravenous | 123mg/kg (123mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: NAUSEA OR VOMITING | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. |
mouse | LD50 | oral | 230mg/kg (230mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958. |
Hazard Codes of Lycorine hydrochloride (CAS NO.2188-68-3): T
Risk Statements: 25
R25: Toxic if swallowed.
Safety Statements: 45
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3