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Proxymetacaine

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Name

Proxymetacaine

EINECS 207-884-9
CAS No. 499-67-2 Density 1.065 g/cm3
PSA 64.79000 LogP 3.13740
Solubility N/A Melting Point 182-183.30C
Formula C16H26 N2 O3 Boiling Point 434.4 °C at 760 mmHg
Molecular Weight 294.394 Flash Point 216.5 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 499-67-2 (proxymetacaine) Hazard Symbols N/A
Synonyms

2-(Diethylamino)ethyl3-amino-4-propoxybenzoate; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethylester; Ophthaine; Proparacaine; Proxymetacaine

 

Proxymetacaine Synthetic route

736870-51-2

3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester)

499-67-2

Proparacain

Conditions
ConditionsYield
With ethanol; platinum Hydrogenation;
616-82-0

3-nitro-4-hydroxybenzoic acid

499-67-2

Proparacain

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3; xylene / Erwaermen des Reaktionsprodukts mit wss.-aethanol. NaOH
2: isopropyl alcohol
3: platinum; ethanol / Hydrogenation
View Scheme
35288-44-9

3-nitro-4-propoxybenzoic acid

499-67-2

Proparacain

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol
2: platinum; ethanol / Hydrogenation
View Scheme
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